Case Report: Dengue hemorrhagic fever with ischemic stroke.
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Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
American Society of Tropical Medicine and Hygiene
Abstract
Several neurological manifestations are recognized in dengue infection, but stroke is a rare complication. We report a case of ischemic stroke in a patient with dengue hemorrhagic fever. A 52-year-old previously healthy male presented with a history of fever for 2 days, and left-sided weakness and numbness of sudden onset. MRI scanning showed a right-sided thalamic lacunar infarct. Diagnosis of dengue fever was made based on leuco-thrombocytopenia, positive dengue nonstructural protein-1 (NS-1) antigen, and positive dengue IgM antibodies. Severity of limb weakness correlated with the critical phase of dengue hemorrhagic fever (DHF). He was discharged home with good recovery from neurological symptoms and disability. Strokes are rare in dengue, and are mainly hemorrhagic strokes related to thrombocytopenia. Ischemic stroke is even rarer. More evidence is needed for confirmation of dengue as a pathogenic mechanism of ischemic stroke.
Description
Indexed in MEDLINE.
Keywords
Dengue, Severe Dengue
Citation
American Journal of Tropical Medicine and Hygiene.2022;106(2):578-581 [Epub 2021 .Nov 15]