In-vitro evaluation of antimicrobial efficacy of the indigenous formulation, Karna Bindu against common pathogens causing otitis infections.
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Date
2019
Journal Title
Journal ISSN
Volume Title
Publisher
International Journal of Scientific Research and Innovative Technology, Volume 6, Issue 7
Abstract
This study investigates the efficacy of the formulation named "Karna Bindlö' which has been used
in indigenous medicinal practices to treat ear infections such as otitis media and otitis externa. The
objectives are to determine the antimicrobial efficacy of Karna Bindu against Aspergillus
niger,Candida alhicans and Pseudomonas aeruginosa and to compare the efficacy of the
indigenous formulation with the conventional antibiotics that are used for the test organisms. By
using the agar well diffusion method, the test organisms were cultivated and the relevant antibiotics
were used as positive controls while sterile distilled water served as the negative control. The antimicrobial assay revealed that Karna Bindu is effective against all three selected
microorganisms. The Minimum Inhibitory Concentrations (MIC) of the formulation for C.
albicans and aeruginosa were recorded as 500 gL/mL, and 750 gL/mL accordingly.
Description
Keywords
ear infections, otitis media, otitis externa, Karna Bindu
Citation
peiris, K.P.P. Wanigasekara, D.N. Sudesh, A.D.H. and Karunarathne, E.D.C. (2019). In-vitro evaluation of antimicrobial efficacy of the indigenous formulation, Karna Bindu against common pathogens causing otitis infections. International Journal of Scientific Research and Innovative Technology, Volume 6, Issue 7