Immunomodulatory activity of three Sri-Lankan medicinal plants used in hepatic disorders
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Date
1991
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
The effects of aqueous extracts of Osbeckia octandra whole plant, Melothria maderaspatana whole plant and Phyllanthus debelis leaves on the human immune system were investigated. The extracts showed strong anticomplement effects on both the classical and alternate pathways of the human complement system in vitro. The effects were dose-dependent and most pronounced in the classical complement pathway assay. The extracts also exhibited a direct dose-dependent inhibition of luminol-induced chemiluminescence of human polymorphonuclear leukocytes upon stimulation with zymosan.
Description
Indexed in MEDLINE
Keywords
Plant Extracts, Plant Extracts-pharmacology, Plants, Medicinal, Plants, Medicinal-chemistry, Phagocytosis-drug effects, Neutrophils-drug effects, Respiration-drug effects, Liver Diseases-drug therapy, Luminol-pharmacology, Adjuvants, Immunologic-pharmacology
Citation
Journal of Ethnopharmacology. 1991; 33(1-2): pp.63-66