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A Cost-of-illness analysis of β-Thalassaemia major in children in Sri Lanka - experience from a tertiary level teaching hospital.

Show simple item record Reed-Embleton, H. Arambepola, S. Dixon, S. Maldonado, B. N. Premawardhena, A. Arambepola, M. Khan, J. A. M. Allen, S. 2020-08-04T05:12:56Z 2020-08-04T05:12:56Z 2020
dc.identifier.citation BMC Pediatrics. 2020;20(1):257. en_US
dc.identifier.issn 1471-2431 (Electronic)
dc.identifier.issn 1471-2431 (Linking)
dc.description Indexed in MEDLINE
dc.description.abstract BACKGROUND: Sri Lanka has a high prevalence of β-thalassaemia major. Clinical management is complex and long-term and includes regular blood transfusion and iron chelation therapy. The economic burden of β-thalassaemia for the Sri Lankan healthcare system and households is currently unknown. METHODS: A prevalence-based, cost-of-illness study was conducted on the Thalassaemia Unit, Department of Paediatrics, Kandy Teaching Hospital, Sri Lanka. Data were collected from clinical records, consultations with the head of the blood bank and a consultant paediatrician directly involved with the care of patients, alongside structured interviews with families to gather data on the personal costs incurred such as those for travel. RESULTS: Thirty-four children aged 2-17 years with transfusion dependent thalassaemia major and their parent/guardian were included in the study. The total average cost per patient year to the hospital was $US 2601 of which $US 2092 were direct costs and $US 509 were overhead costs. Mean household expenditure was $US 206 per year with food and transport per transfusion ($US 7.57 and $US 4.26 respectively) being the highest cost items. Nine (26.5%) families experienced catastrophic levels of healthcare expenditure (> 10% of income) in the care of their affected child. The poorest households were the most likely to experience such levels of expenditure. CONCLUSIONS: β-thalassaemia major poses a significant economic burden on health services and the families of affected children in Sri Lanka. Greater support is needed for the high proportion of families that suffer catastrophic out-of-pocket costs. KEYWORDS: Children; Cost-of-illness; Sri Lanka; Thalassaemia. en_US
dc.language.iso en_US en_US
dc.publisher BioMed Central. en_US
dc.subject Thalassemia en_US
dc.subject beta-Thalassemia en
dc.subject beta-Thalassemia-therapy en
dc.subject Health Expenditures en
dc.subject Hospitals, Teaching en
dc.subject Child en
dc.subject Sri Lanka en
dc.title A Cost-of-illness analysis of β-Thalassaemia major in children in Sri Lanka - experience from a tertiary level teaching hospital. en_US
dc.type Article en_US

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