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Contribution of rickettsioses in Sri Lankan patients with fever who responded to empirical doxycycline treatment

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dc.contributor.author Premaratna, R. en_US
dc.contributor.author Rajapakse, R.P.V.J. en_US
dc.contributor.author Chandrasena, T.G.A.N. en_US
dc.contributor.author Nanayakkara, D.M. en_US
dc.contributor.author Bandara, N.K.B.K.R.G.W. en_US
dc.contributor.author Kularatne, S.A.M. en_US
dc.contributor.author Eremeeva, M.E. en_US
dc.contributor.author Dasch, G.A. en_US
dc.contributor.author de Silva, H.J. en_US
dc.date.accessioned 2014-10-29T09:28:12Z
dc.date.available 2014-10-29T09:28:12Z
dc.date.issued 2010 en_US
dc.identifier.citation Transactions of the Royal Society of Tropical Medicine and Hygiene; 104(5): pp.368-70 en_US
dc.identifier.issn 0035-9203 (Print) en_US
dc.identifier.issn 1878-3503 (Electronic) en_US
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/1961
dc.description.abstract Twenty-eight febrile Sri Lankan patients with undiagnosed fever for 7 days after hospital admission, who responded to empirical treatment with doxycycline, were retrospectively investigated using microimmunofluorescence assay to verify whether they had rickettsial infection. Eleven (39%) patients were confirmed as having spotted fever group rickettsioses and 10 (36%) as having Orientia tsutsugamushi. Seven were negative for all tests. This suggests that greater use of doxycycline appears justified for patients with undiagnosed fever in settings where rickettsial diseases are endemic or re-emerging with inadequate diagnostic facilities.
dc.publisher Oxford University Press en_US
dc.title Contribution of rickettsioses in Sri Lankan patients with fever who responded to empirical doxycycline treatment en_US
dc.type Article en_US
dc.identifier.department Medicine en_US
dc.identifier.department Parasitology en_US
dc.creator.corporateauthor Royal Society of Tropical Medicine and Hygiene en_US


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