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Functional abdominal pain disorders in children

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dc.contributor.author Rajindrajith, S. en_US
dc.contributor.author Zeevenhooven, J. en_US
dc.contributor.author Devanarayana, N.M. en_US
dc.contributor.author Perera, B.J.C. en_US
dc.contributor.author Benninga, M.A. en_US
dc.date.accessioned 2018-03-07T08:55:54Z en_US
dc.date.available 2018-03-07T08:55:54Z en_US
dc.date.issued 2018 en_US
dc.identifier.citation Expert Review of Gastroenterology & Hepatology. 2018;12(4):369-390. en_US
dc.identifier.issn 1747-4124 (Print) en_US
dc.identifier.issn 1747-4132 (Electronic) en_US
dc.identifier.issn 1747-4124 (Linking) en_US
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/18621 en_US
dc.description Indexed In MEDLINE en_US
dc.description.abstract Chronic abdominal pain is a common problem in pediatric practice. The majority of cases fulfill the Rome IV criteria for functional abdominal pain disorders (FAPDs). At times, these disorders may lead to rather serious repercussions. Area covered: We have attempted to cover current knowledge on epidemiology, pathophysiology, risk factors related to pathophysiology, clinical evaluation and management of children with FAPDs. Expert commentary: FAPDs are a worldwide problem with a pooled prevalence of 13.5%. There are a number of predisposing factors and pathophysiological mechanisms including stressful events, child maltreatment, visceral hypersensitivity, altered gastrointestinal motility and change in intestinal microbiota. It is possible that the environmental risk factors intricately interact with genes through epigenetic mechanisms to contribute to the pathophysiology. The diagnosis mainly depends on clinical evaluation. Commonly used pharmacological interventions do not play a major role in relieving symptoms. Centrally directed, nonpharmacological interventions such as hypnotherapy and cognitive behavioral therapy have shown both short and long term efficacy in relieving pain in children with FAPDs. However, these interventions are time consuming and need specially trained staff and therefore, not currently available at grass root level. Clinicians and researchers should join hands in searching for more pragmatic and effective therapeutic modalities to improve overall care of children with FAPDs. en_US
dc.language.iso en_US en_US
dc.publisher Taylor & Francis en_US
dc.subject Abdominal pain en_US
dc.subject.mesh Child en
dc.title Functional abdominal pain disorders in children en_US
dc.type Article en_US


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