Browsing Journal/Magazine Articles by Author "Gunawardena, N.K."

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Adjusting for spatial variation when assessing individual-level risk: A case-study in the epidemiology of snake-bite in Sri Lanka

Ediriweera, D.S.; Kasturiratne, A.; Pathmeswaran, A.; Gunawardena, N.K.; Jayamanne, S.F.; Murray, K.; Iwamura, T.; Lalloo, D.G.; de Silva, H.J.; Diggle, P.J. (Public Library of Science, 2019)

BACKGROUND:Health outcomes and causality are usually assessed with individual level sociodemographic variables. Studies that consider only individual-level variables can suffer from residual confounding. This can result ...
Bihar's pioneering school-based deworming programme: lessons learned in deworming over 17 million Indian school-age children in one sustainable campaign.

Drake, L.J.; Singh, S.; Mishra, C.K.; Sinha, A.; Kumar, S.; Bhushan, R.; Hollingsworth, T.D.; Appleby, L.J.; Kumar, R.; Sharma, K.; Kumar, Y.; Raman, S.; Chakrabarty, S.; Kihara, J.H.; Gunawardena, N.K.; Hollister, G.; Kumar, V.; Ankur, A.; Prasad, B.; Ramachandran, S.; Fishbane, A.; Makkar, P. (San Francisco, CA : Public Library of Science, 2015)
A Case of imported malaria: the first report of Plasmodium malariae infection in Sri Lanka after 37 years

Hapuarachchi, H.A.C.; Gunawardena, N.K.; Senevirathne, M.P.; Abeyewickreme, W.; de Silva, N.R. (Sri Lanka Medical Association, 2008)

We report a case of Plasmodium falciparum and P. malariae mixed infection in a patient who had been living in Malawi. This is the first case of P. malariae reported in Sri Lanka in 4 decades. The presence of both parasites ...
Chemotactic response of Brugia pahangi infective larvae to jird serum in vitro

Gunawardena, N.K.; Fujimaki, Y.; Aoki, Y. (Springer International, 2003)

The Brugia pahangi infective larval response to jird serum was studied using an agar plate assay. Larvae placed onto the agar remained at the same place for 60 min. Once the larvae were stimulated by serum, more than 95% ...
Correction: Double burden of maternal and child malnutrition and socioeconomic status in urban Sri Lanka.

Shinsugi, C.; Gunasekara, D.; Gunawardena, N.K.; Subasinghe, W.; Miyoshi, M.; Kaneko, S.; Takimoto, H. (Public Library of Science, 2020)

[This corrects the article DOI: 10.1371/journal.pone.0224222.]. Erratum for Double burden of maternal and child malnutrition and socioeconomic status in urban Sri Lanka. PLoS One.2019;14(10):e0224222.
Differential effects of diethylcarbamazine, tetracycline and the combination on Brugia pahangi adult females in vitro

Gunawardena, N.K.; Fujimaki, Y.; Aoki, Y.; Mishima, N.; Ezaki, T.; Uni, S.; Kimura, E. (Elsevier, 2005)

Anti-filarial effects of diethylcarbamazine (DEC), tetracycline (TC) and the combination on Brugia pahangi adult females were studied in 7-day cell-free culture, in terms of microfilaria release, parasite motility, MTT ...
The Diversity of Human Dirofilariasis in Western Sri Lanka

Chandrasena, T.G.A.N.; Premaratna, R.; Mallawaarachchi, C.H.; Gunawardena, N.K.; Gunathilaka, P.A.D.H.N.; Abeyewickrama, W.Y.; de Silva, N.R. (Hindawi Pub. Co, 2019)

BACKGROUND:Human dirofilariasis is an emerging zoonosis in many countries. Dirofilariasis caused by Dirofilaria repens may present with diverse clinical manifestations in humans due to aberrant localization of worm lesions ...
Double burden of maternal and child malnutrition and socioeconomic status in urban Sri Lanka

Shinsugi, C.; Gunasekara, D.; Gunawardena, N.K.; Subasinghe, W.; Miyoshi, M.; Kaneko, S.; Takimoto, H. (Public Library of Science, 2019)

Child malnutrition and maternal obesity are serious public health issues in Sri Lanka. This study explores the associations between socioeconomic status and the double burden of malnutrition among school-aged children and ...
Effect of repeated mass chemotherapy for filariasis control on soil-transmitted helminth infections in Sri Lanka

Gunawardena, N.K.; Amarasekera, N.D.D.M.; Pathmeswaran, A.; de Silva, N.R. (Sri Lanka Medical Association, 2008)

BACKGROUND: In July 2006 Sri Lanka completed 5 rounds of annual mass drug administration (MDA) with diethylcarbamazine citrate (DEC) and albendazole as part of its national programme for elimination of lymphatic filariasis ...
Epidemiology of aerophagia in children and adolescents: A systematic review and meta-analysis

Rajindrajith, S.; Gunawardane, D.; Kuruppu, C.; Dharmaratne, S.D.; Gunawardena, N.K.; Devanarayana, N.M. (Public Library of Science, 2022)

Background: Aerophagia is a common functional gastrointestinal disorder among children. The disease leads to symptoms related to air in the intestine leading to burping, abdominal distension, and excessive flatus. We aimed ...
Epidemiology of bancroftian filariasis in three suburban areas of Matara, Sri Lanka

Weerasooriya, M.V.; Weerasooriya, T.R.; Gunawardena, N.K.; Samarawickrema, W.A.; Kimura, E. (Academic Press, 2001)

The epidemiological parameters of bancroftian filariasis were investigated in three suburbs of Matara, within the south-western coastal belt of SriLanka where the disease is endemic. The overall prevalence of microfilaraemia ...
Epidemiology of irritable bowel syndrome in children and adolescents in Asia

Devanarayana, N.M.; Rajindrajith, S.; Pathmeswaran, A.; Abeygunasekara, C.; Gunawardena, N.K.; Benninga, M.A. (Lippincott Williams and Wilkins, 2015)

OBJECTIVES: Several cross-sectional surveys have been conducted to study the prevalence of irritable bowel syndrome (IBS) in children. The aim of the present study was to conduct a systematic review and a meta-analysis of ...
Evaluating spatiotemporal dynamics of snakebite in Sri Lanka: Monthly incidence mapping from a national representative survey sample

Ediriweera, D.S.; Kasturiratne, A.; Pathmeswaran, A.; Gunawardena, N.K.; Jayamanne, S.F.; Murray, K.; Iwamura, T.; Isbister, G.; Dawson, A.; Lalloo, D.G.; de Silva, H.J.; Diggle, P.J. (Public Library of Science, 2021)

BACKGROUND: Snakebite incidence shows both spatial and temporal variation. However, no study has evaluated spatiotemporal patterns of snakebites across a country or region in detail. We used a nationally representative ...
Evaluating temporal patterns of snakebite in Sri Lanka: the potential for higher snakebite burdens with climate change

Ediriweera, D.S.; Diggle, P.J.; Kasturiratne, A.; Pathmeswaran, A.; Gunawardena, N.K.; Jayamanne, S.K.; Isbister, G.K.; Dawson, A.; Lalloo, D.G.; de Silva, H.J. (Oxford University Press, 2018)

BACKGROUND: Snakebite is a neglected tropical disease that has been overlooked by healthcare decision makers in many countries. Previous studies have reported seasonal variation in hospital admission rates due to snakebites ...
The Global burden of snakebite: a literature analysis and modelling based on regional estimates of envenoming and deaths

Kasturiratne, A.; Wickremasinghe, A.R.; de Silva, N.; Gunawardena, N.K.; Pathmeswaran, A.; Premaratna, R.; Savioli, L.; Lalloo, D.G.; de Silva, H.J. (Public Library of Science, 2008)

BACKGROUND: Envenoming resulting from snakebites is an important public health problem in many tropical and subtropical countries. Few attempts have been made to quantify the burden, and recent estimates all suffer from ...
Health seeking behavior following snakebites in Sri Lanka: Results of an island wide community based survey

Ediriweera, D.S.; Kasturiratne, A.; Pathmeswaran, A.; Gunawardena, N.K.; Jayamanne, S.F.; Lalloo, D.G.; de Silva, H.J. (Public Library of Science, 2017)

INTRODUCTION: Sri Lanka has a population of 21 million and about 80,000 snakebites occur annually. However, there are limited data on health seeking behavior following bites. We investigated the effects of snakebite and ...
Human infection with Wuchereria bancrofti in Matara, Sri Lanka: the use, in parallel, of an ELISA to detect filaria-specific IgG4 in urine and of ICT card tests to detect filarial antigen in whole blood

Weerasooriya, M.V.; Itoh, M.; Mudalige, M.P.; Qiu, X.G.; Kimura, E.; Gunawardena, N.K.; Fujimaki, Y. (Academic Press, 2003)

The ICT card test to detect circulating filarial antigen and an ELISA that detects filaria-specific urinary IgG(4) were each used to screen 473 subjects from a community in Sri Lanka where Wuchereria bancrofti is endemic. ...
Impact of helminth infection on childhood allergic diseases in an area in transition from high to low infection burden

Amarasekera, M.; Gunawardena, N.K.; de Silva, N.R.; Douglass, J.A.; O Hehir, R.E.; Weerasinghe, A. (Asia Pacific Association of Allergy, Asthma and Clinical Immunology, 2012)

BCKGROUND: The effect of helminth infections on allergic diseases is still inconclusive. Furthermore, the effect of helminth infections on childhood allergic diseases in a tropical area where prevalence of helminth ...
Integrated school-based surveillance for soil-transmitted helminth infections and lymphatic filariasis in Gampaha district, Sri Lanka

Gunawardena, S.; Gunawardena, N.K.; Kahathuduwa, G.; Karunaweera, ND.; de Silva, N.R.; Ranasinghe, U.B.; Samarasekara, S.D.; Nagodavithana, K.C.; Rao, R.U.; Rebollo, M.P.; Weil, G.J. (American Society of Tropical Medicine and Hygiene, 2014)

We explored the practicality of integrating surveillance for soil-transmitted helminthiasis (STH, assessed by Kato-Katz) with transmission assessment surveys for lymphatic filariasis (LF) in two evaluation units (EUs) in ...
Introduction to geographic information system

Gunawardena, N.K. (Sri Lanka College of Microbiologists, 2014)

There is no single definition for geographic information system (GIS). There are many working definitions and most of them are acceptable for understanding purpose. A geographic information system is a computer system that ...

Browsing Journal/Magazine Articles by Author "Gunawardena, N.K."

Browsing Journal/Magazine Articles by Author "Gunawardena, N.K."

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