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Browsing Journal/Magazine Articles by Title

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  • The gastroprotective effect of ethyl acetate fraction of hot water extract of Trichosanthes cucumerina Linn and its underlying mechanisms 
    Karunakaran, R.; Ira Thabrew, M.; Thammitiyagodage, G.M.; Galhena, P.B.; Menuka Arawwawala, L.D.A. (BioMed Central, 2017)
    BACKGROUND: Antacids, anticholinergic drugs, histamine H2- receptor antagonists and irreversible proton pump inhibitors have been used for the treatment of gastric ulcers. However, prolonged use of these drugs may lead to ...
  • Gatekeeper training for vendors to reduce pesticide self-poisoning in rural South Asia: a study protocol for a stepped-wedge cluster randomised controlled trial 
    Weerasinghe, M.; Pearson, M.; Turner, N.; Metcalfe, C.; Gunnell, D.J.; Agampodi, S.; Hawton, K.; Agampodi, T.; Miller, M.; Jayamanne, S.; Parker, S.; Sumith, J.A.; Karunarathne, A.; Dissanayaka, K.; Rajapaksha, S.; Rodrigo, D.; Abeysinghe, D.; Piyasena, C.; Kanapathy, R.; Thedchanamoorthy, S.; Madsen, L.B.; Konradsen, F.; Eddleston, M. (BMJ Publishing Group Ltd, 2022)
    Introduction: Pesticide self-poisoning kills an estimated 110 000-168 000 people worldwide annually. Data from South Asia indicate that in 15%-20% of attempted suicides and 30%-50% of completed suicides involving pesticides ...
  • GDF15 linked to maternal risk of nausea and vomiting during pregnancy 
    Fejzo, M.; Rocha, N.; Cimino, I.; Lockhart, S.M.; Petry, C.J.; Kay, R.G.; Burling, K.; Barker, P.; George, A.L.; Yasara, N.; Premawardhena, A.; Gong, S.; Cook, E.; Rimmington, D.; Rainbow, K.; Withers, D.J.; Cortessis, V.; Mullin, P.M.; MacGibbon, K.W.; Jin, E.; Kam, A.; Campbell, A.; Polasek, O.; Tzoneva, G.; Gribble, F.M.; Yeo, G.S.H.; Lam, B.Y.H.; Saudek, V.; Hughes, I.A.; Ong, K.K.; Perry, J.R.B.; Sutton, C.A.; Baumgarten, M.; Welsh, P.; Sattar, N.; Smith, G.C.S.; Charnock- Jones, D.S.; Coll, A.P.; Meek, C.L.; Mettananda, S.; Hayward, C.; Mancuso, N.; O'Rahilly, S. (Nature Pub. Group, 2024)
    GDF15, a hormone acting on the brainstem, has been implicated in the nausea and vomiting of pregnancy (NVP) including its most severe form, Hyperemesis Gravidarum (HG), but a full mechanistic understanding is lacking [1-4]. ...
  • GDF15 molecule is responsible for low body mass index in children with thalassaemia 
    Mettananda, S. (Sri Lanka College of Paediatricians, 2024)
    No abstract available
  • Gender disparity as a threat to the mental well-being of young Sri Lankan women. 
    Chandradasa, M.; Rathnayake, L.C. (Cambridge University Press, 2019)
    ABSTRACT:Sri Lanka ranks highest in the region for human development. Despite producing the first female head of state in the world, the country has failed to achieve substantial gains in the gender inequality indices in ...
  • Gender distribution of editors in psychiatry journals of South Asia 
    Arafat, S.M.Y.; Amin, R.; Baminiwatta, A.; Hussain, F.; Singh, R.; Kar, S.K.; Mubashir, A.S. (lsevier/North-Holland Biomedical Press, 2022)
    No abstract available
  • Gender dysphoria and morbid sexual jealousy in an adolescent. 
    Rathnayake, L.C.; Kuruppuarachchi, C.; Abeyrathne, M.; de Silva Rajaratne, P.K.D.H.J.L.; Chandradasa, M.; Kuruppuarachchi, K.A.L.A. (Kandy Society of Medicine, 2022)
    Gender dysphoria is the psychological distress that occurs when an individual’s biologically determined sex and gender identity do not align. Jealousy is likely to occur in any form of intimate partnership, irrespective ...
  • Gender parity among psychiatrists: The trends and current status in Sri Lanka 
    Baminiwatta, A.; Alahakoon, H.; Kasturi Mudali, A. (Elsevier, 2021)
    No abstract available
  • Gene flow patterns among Aedes aegypti (Diptera: Culicidae) populations in Sri Lanka 
    Fernando, H.S.D.; Hapugoda, M.; Perera, R.; Black Iv, W.C.; de Silva, B.G.D.N.K. (MDPI AG, 2020)
    ABSTRACT:In Sri Lanka, dengue is the most serious arboviral disease. Recent increases in dengue cases suggest a higher infection rate and spread of the disease to new areas. The present study explores gene flow patterns ...
  • Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci 
    de Las Fuentes, L.; Sung, Y. J.; Noordam, R.; Winkler, T.; Feitosa, M.F.; Schwander, K.; Bentley, A.R.; Brown, M.R.; Guo, X.; Manning, A.; Chasman, D.I.; Aschard, H.; Bartz, T. M.; Bielak, L.F.; Campbell, A.; Cheng, C.Y.; Dorajoo, R.; Hartwig, F. P.; Horimoto, A.R.V.R.; Li, C.; Li-Gao, R.; Liu, Y.; Marten, J.; Musani, S.K.; Ntalla, I.; Rankinen, T.; Richard, M.; Sim, X.; Smith, A.V.; Tajuddin, S.M.; Tayo, B.O.; Vojinovic, D.; Warren, H.R.; Xuan, D.; Alver, M.; Boissel, M.; Chai, J.F.; Chen, X.; Christensen, K.; Divers, J.; Evangelou, E.; Gao, C.; Girotto, G.; Harris, S.E.; He, M.; Hsu, F.C.; Kühnel, B.; Laguzzi, F.; Li, X.; Lyytikäinen, L. P.; Nolte, I. M.; Poveda, A.; Rauramaa, R.; Riaz, M.; Rueedi, R.; Shu, X.O.; Snieder, H.; Sofer, T.; Takeuchi, F.; Verweij, N.; Ware, E.B.; Weiss, S.; Yanek, L.R.; Amin, N.; Arking, D.E.; Arnett, D.K.; Bergmann, S.; Boerwinkle, E.; Brody, J.A.; Broeckel, U.; Brumat, M.; Burke, G.; Cabrera, C.P.; Canouil, M.; Chee, M.L.; Chen, Y. I.; Cocca, M.; Connell, J.; de Silva, H.J.; de Vries, P. S.; Eiriksdottir, G.; Faul, J.D.; Fisher, V.; Forrester, T.; Fox, E.F.; Friedlander, Y.; Gao, H.; Gigante, B.; Giulianini, F.; Gu, C.C.; Gu, D.; Harris, T. B.; He, J.; Heikkinen, S.; Heng, C. K.; Hunt, S.; Ikram, M. A.; Irvin, M.R.; Kähönen, M.; Kavousi, M.; Khor, C.C.; Kilpeläinen, T.O.; Koh, W.P.; Komulainen, P.; Kraja, A.T.; Krieger, J.E.; Langefeld, C. D.; Li, Y.; Liang, J.; Liewald, D.C.M.; Liu, C.T.; Liu, J.; Lohman, K.K.; Mägi, R.; McKenzie, C.A.; Meitinger, T.; Metspalu, A.; Milaneschi, Y.; Milani, L.; Mook-Kanamori, D.O.; Nalls, M.A.; Nelson, C.P.; Norris, J. M.; O'Connell, J.; Ogunniyi, A.; Padmanabhan, S.; Palmer, N.D.; Pedersen, N. L.; Perls, T.; Peters, A.; Petersmann, A.; Peyser, P. A.; Polasek, O.; Porteous, D. J.; Raffel, L. J.; Rice, T. K.; Rotter, J.I.; Rudan, I.; Rueda-Ochoa, O.L.; Sabanayagam, C.; Salako, B. L.; Schreiner, P.J.; Shikany, J.M.; Sidney, S.S.; Sims, M.; Sitlani, C.M.; Smith, J. A.; Starr, J. M.; Strauch, K.; Swertz, M. A.; Teumer, A.; Tham, Y. C.; Uitterlinden, A.G.; Vaidya, D.; van der Ende, M.Y.; Waldenberger, M.; Wang, L.; Wang, Y. X.; Wei, W.B.; Weir, D.R.; Wen, W.; Yao, J.; Yu, B.; Yu, C.; Yuan, J. M.; Zhao, W.; Zonderman, A.B.; Becker, D.M.; Bowden, D.W.; Deary, I. J.; Dörr, M.; Esko, T.; Freedman, B. I.; Froguel, P.; Gasparini, P.; Gieger, C.; Jonas, J.B.; Kammerer, C.M.; Kato, N.; Lakka, T. A.; Leander, K.; Lehtimäki, T.; Lifelines Cohort Study; Magnusson, P. K. E.; Marques-Vidal, P.; Penninx, B. W. J. H.; Samani, N. J.; van der Harst, P.; Wagenknecht, L. E.; Wu, T.; Zheng, W.; Zhu, X.; Bouchard, C.; Cooper, R. S.; Correa, A.; Evans, M. K.; Gudnason, V.; Hayward, C.; Horta, B. L.; Kelly, T. N.; Kritchevsky, S. B.; Levy, D.; Palmas, W. R.; Pereira, A. C.; Province, M. M.; Psaty, B. M.; Ridker, P. M.; Rotimi, C. N.; Tai, E. S.; van Dam, R. M.; van Duijn, C. M.; Wong, T. Y.; Rice, K.; Gauderman, W. J.; Morrison, A. C.; North, K. E.; Kardia, S. L. R.; Caulfield, M. J.; Elliott, P.; Munroe, P. B.; Franks, P. W.; Rao, D. C.; Fornage, M. (Stockton Press., 2021)
    ABSTRACT:Educational attainment is widely used as a surrogate for socioeconomic status (SES). Low SES is a risk factor for hypertension and high blood pressure (BP). To identify novel BP loci, we performed multi-ancestry ...
  • Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci 
    de Las, F.L.; Schwande, K.L.; Brown, M.R.; Bentley, A.R.; Winkler, T.W.; Sung, Y.J.; Munroe, P.B.; Miller, C.L.; Aschard, H.; Aslibekyan, S.; Bartz, T.M.; Bielak, L.F.; Chai, J.F.; Cheng, C.Y.; Dorajoo, R.; Feitosa, M.F.; Guo, X.; Hartwig, F.P.; Horimoto, A.; Kolčić, I.; Lim, E.; Liu, Y.; Manning, A.K.; Marten, J.; Musani, S.K.; Noordam, R.; Padmanabhan, S.; Rankinen, T.; Richard, M.A.; Ridker, P.M.; Smith, A.V.; Vojinovic, D.; Zonderman, A.B.; Alver, M.; Boissel, M.; Christensen, K.; Freedman, B.I.; Gao, C.; Giulianini, F.; Harris, S.E.; He, M.; Hsu, F.C.; Kühnel, B.; Laguzzi, F.; Li, X.; Lyytikäinen, L.P.; Nolte, I.M.; Poveda, A.; Rauramaa, R.; Riaz, M.; Robino, A.; Sofer, T.; Takeuchi, F.; Tayo, B.O.; van der, M.P.J.; Verweij, N.; Ware, E.B.; Weiss, S.; Wen, W.; Yanek, L.R.; Zhan, Y.; Amin, N.; Arking, D.E.; Ballantyne, C.; Boerwinkle, E.; Brody, J.A.; Broeckel, U.; Campbell, A.; Canouil, M.; Chai, X.; Chen, Y.I.; Chen, X.; Chitrala, K.N.; Concas, M.P.; de Faire, U.; de Mutsert, R.; de Silva, H.J.; de Vries, P.S.; Do, A.; Faul, J.D.; Fisher, V.; Floyd, J.S.; Forrester, T.; Friedlander, Y.; Girotto, G.; Gu, C.C.; Hallmans, G.; Heikkinen, S.; Heng, C.K.; Homuth, G.; Hunt, S.; Ikram, M.A.; Jacobs, D.R.J.R.; Kavousi, M.; Khor, C.C.; Kilpeläinen, T.O.; Koh, W.P.; Komulainen, P.; Langefeld, C.D.; Liang, J.; Liu, K.; Liu, J.; Lohman, K.; Mägi, R.; Manichaikul, A.W.; McKenzie, C.A.; Meitinger, T.; Milaneschi, Y.; Nauck, M.; Nelson, C.P.; O'Connell, J.R.; Palmer, N.D.; Pereira, A.C.; Perls, T.; Peters, A.; Polašek, O.; Raitakari, O.T.; Rice, K.; Rice, T.K.; Rich, S.S.; Sabanayagam, C.; Schreiner, P.J.; Shu, X.; Sidney, S.; Sims, M.; Smith, J.A.; Starr, J.M.; Strauch, K.; Tai, E.S.; Taylor, K.D.; Tsai, M.Y.; Uitterlinden, A.G.; Heemst, D.V.; Waldenberger, M.; Wang, Y.; Wei, W.; Wilson, G.; Xuan, D.; Yao, J.; Yu, C.; Yuan, J.; Zhao, W.; Becker, D.M.; Bonnefond, A.; Bowden, D.W.; Cooper, R.S.; Deary, I.J.; Divers, J.; Esko, T.; Franks, P.W.; Froguel, P.; Gieger, C.; Jonas, J.B.; Kato, N.; Lakka, T.A.; Leander, K.; Lehtimäki, T.; Magnusson, P.K.E.; North, K.E.; Ntalla, I.; Penninx, B.; Samani, N.J.; Snieder, H.; Spedicati, B.; Harst, P.V.D.; Völzke, H.; Wagenknecht, L.E.; Weir, D.R.; Wojczynski, M.K.; Wu, T.; Zheng, W.; Zhu, X.; Bouchard, C.; Chasman, D.I.; Evans, M.K.; Fox, E.R.; Gudnason, V.; Hayward, C.; Horta, B.L.; Kardia, S.L.R.; Krieger, J.E.; Mook-Kanamori, D.O.; Peyser, P.A.; Province, M.M.; Psaty, B.M.; Rudan, I.; Sim, X.; Smith, B.H.; Dam, R.M.V.; Duijn, C.M.V.; Wong, T.Y.; Arnett, D.K.; Rao, D.C.; Gauderman, J.; Liu, C.; Morrison, A.C.; Rotter, J.I.; Fornage, M. (Frontiers Research Foundation, 2023)
    INTRODUCTION: Educational attainment, widely used in epidemiologic studies as a surrogate for socioeconomic status, is a predictor of cardiovascular health outcomes. METHODS: A two-stage genome-wide meta-analysis of ...
  • Geneder differences in undergraduate medical examination results in Sri Lanka 
    de Silva, N.R.; Thabrew, M.I.; Saparamadu, P.A.M.; Jayawardena, D.R.K.C.; Arachchige, A.A.; Weerawardhane, M.; Gunawardene, Y.I.N.S. (Sri Lanka Medical Association, 2000)
    OBJECTIVE: To identify possible gender related differences in performance at undergraduate medical examinations in Sri Lanka. STUDY DESIGN AND METHODS: Results of examinations conducted by the faculty of medicine, University ...
  • General practice is "different": a qualitative study of adaptation experiences of East Staffordshire general practice speciality trainees 
    Perera, D.P.; Mohanna, K. (Taylor & Francis-Radcliffe Medical Press, 2021)
    ABSTRACT: Undergraduate medical education and foundation training are still largely hospital based. General practice trainees also spend nearly half of their speciality training in hospitals. Aims: To explore adaptation ...
  • General practitioners requesting radiological investigations: a qualitative study of the perceptions of radiologists 
    Ramanayake, R.P.J.C.; Perera, D.P.; Basnayake, B.M.T.K. (College of General Practitioners of Sri Lanka, 2017)
    BACKGROUND: General practice provides person centred, continuing, comprehensive and coordi- nated whole person care to individuals and families in their communities. Patients present with early nonspecific symptoms of ...
  • Genetic and environmental risk for asthma in children aged 5-11 years 
    Karunasekera, K.A.W.; Perera, K.P.J.; Perera, M.T.P.R.; Abeynarayana, J. (Sri Lanka College of Paediatricians, 2005)
    DESIGN: A cross sectional analytical study. METHOD: Data were collected from children aged 5-11 years in 3 schools in Gampaha District. 441 children with asthma and 1510 without asthma were evaluated for following risk ...
  • Genetic and epigenetic therapies for β-Thalassaemia by altering the expression of α-globin gene 
    Mettananda, S. (Frontiers Media S.A, 2021)
    β-Thalassaemia is caused by over 300 mutations in and around the β-globin gene that lead to impaired synthesis of β-globin. The expression of α-globin continues normally, resulting in an excess of α-globin chains within ...
  • Genetic and metabolic aspects of non-alcoholic fatty liver disease (NAFLD) pathogenicity 
    Samarasinghe, S.M.; Hewage, A.S.; Siriwardana, R.C.; Tennekoon, K.H.; Niriella, M.A.; de Silva, S. (Springer, 2023)
    BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease showing a risingprevalence globally. Genetic predisposition plays a key role in the development and progression of the disease ...
  • Genetic associations of inflammatory bowel disease in a South Asian population 
    Niriella, M.A.; Liyanage, I.K.; Kodisinghe, S.K.; Silva, A.P.; Rajapakshe, N.; Nanayakkara, S.D.; Luke, D.; Silva, T.; Nawarathne, M.; Peiris, R.K.; Kalubovila, U.P.; Kumarasena, S.R.; Dissanayake, V.H.W.; Jayasekara, R.W.; de Silva, H.J. (Baishideng Publishing Group, 2018)
    AIM: To estimate prevalence and phenotypic associations of selected inflammatory bowel disease (IBD)-associated genetic variants among Sri Lankan patients. METHODS: A case study of histologically confirmed ulcerative colitis ...
  • Genetic determinants of jaundice and gallstones in haemoglobin E beta thalassaemia 
    Premawardhena, A.P.; Fisher, C.A.; Fathihu, F.; de Silva, S.; Perera, W.; Peto, T.E.; Olivieri, N.F.; Weatherall, D.J. (2001)
    Chronic hyperbilirubinaemia, gallstone formation, and gall bladder disease are unusually common in people with haemoglobin E beta thalassaemia in Sri Lanka. To determine whether this has a genetic basis we compared the ...
  • Genetic diversity of Leishmania donovani isolates from cutaneous lesions of military personnel in the Mullaitivu and Kilinochchi districts of the Northern Province, Sri Lanka 
    Wijerathna, T.; Gunathilaka, N.; Semege, S.; Pathirana, N.; Rodrigo, W.; Fernando, D. (Wolters Kluwer, 2022)
    Objective: To compare the DNA sequences of Leishmania (L.) donovani isolated from individuals in two districts of the Northern Province with other parts of Sri Lanka and neighboring countries. Methods: Samples were collected ...

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