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Browsing Medicine by Title

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  • Epidemiology of goitres in Sri Lanka with Geographic Information System Mapping: a population based cross sectional study 
    Fernando, R.; Chandrasinghe, P.C.; Nandasena, S.; Pathmeswaran, A. (Jaypee Publishers, 2015)
    BACKGROUND: Sri Lanka is considered an endemic region for goiter. Early researchers have suggested the existence of a goiter belt based on rainfall pattern. Subsequent studies done in school children have challenged this ...
  • Epidemiology of hypertension in an urban population of Sri Lanka 
    Kasturiratne, A.; Pinidiyapathirage, M.J.; Pathmeswaran, A.; Kato, N.; Wickremasinghe, A.R.; de Silva, H.J. (Sri Lanka Medical Association, 2011)
    INTRODUCTION AND OBJECTIVES: To describe the epidemiology of hypertension in 35-64 year old adults resident in Ragama Medical Officer of Health area in the Gampaha district, Sri Lanka. Methods: The Ragama Health Study is ...
  • Epidemiology of hypertension in an urban Sri Lankan population 
    Kasturiratne, A.; Warnakulasuriya, T.; Pinidiyapathirage, J.; Kato, N.; Wickremasinghe, A.R.; Pathmeswaran, A. (BMJ Publishing Group, 2011)
    INTRODUCTION: Hypertension is a common risk factor for cardiovascular disease. In Sri Lanka, despite the existence of a universal free health system, services are not available for routine screening of hypertension in the ...
  • The epidemiology of irritable bowel syndrome among children and adolescents in Asia: a systematic review 
    Rajindrajith, S.; Gunawardena, N.K.; Abeygunasekara, C.; Devanarayana, N.M. (Belgian Society of Paediatric Gastroenterology, Hepatology and Nutrition (BeSPGHAN),, 2013)
    Aims: Irritable bowel syndrome (IBS) is characterized by chronic abdominal pain and changing bowel habits including frequency and consistency. The aim of this study was to systematically review published literature on ...
  • Epidemiology of irritable bowel syndrome in children and adolescents in Asia 
    Devanarayana, N.M.; Rajindrajith, S.; Pathmeswaran, A.; Abeygunasekara, C.; Gunawardena, N.K.; Benninga, M.A. (Lippincott Williams and Wilkins, 2015)
    OBJECTIVES: Several cross-sectional surveys have been conducted to study the prevalence of irritable bowel syndrome (IBS) in children. The aim of the present study was to conduct a systematic review and a meta-analysis of ...
  • Epidemiology of multidrug-resistant Enterobacteriaceae in Sri Lanka: First evidence of bla KPC harboring Klebsiella pneumoniae. 
    Kumudunie, W.G.M.; Wijesooriya, L.I.; Namalie, K.D.; Sunil-Chandra, N.P.; Wijayasinghe, Y.S. (Elsevier., 2020)
    BACKGROUND: Extended-spectrum β-lactamase producing Enterobacteriaceae (ESBL-PE) and carbapenem-resistant Enterobacteriaceae (CRE) are disseminated worldwide posing a serious public health concern. Although, the presence ...
  • Epidemiology of non- alcoholic fatty liver disease (NAFLD) in an urban Sri Lankan population 
    Dassanayake, A.S.; Rajindrajith, S.; Kasturiratne, A.; Kalubowila, U.; de Silva, A.P.; Mizoue, T.; Makaya, M.; de Silva, H.J. (Sri Lanka Medical Association, 2008)
    BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is increasing in the Asia-Pacific region. NAFLD can progress from simple steatosis, through steatohepatitis to advanced hepatic fibrosis, cirrhosis and hepatoma. Its ...
  • Epidemiology of Non-Alcoholic Fatty Liver Disease (NAFLD) among adults in an urban Sri Lankan community 
    Dassanayake, A.S.; Rajindrajith, S.; Kasturiratne, A.; Kalubowila, U.; de Silva, A.P.; Mizoue, T.; Makaya, M.; de Silva, H.J. (American Gastroenterological Association(AGA) Institute, Published by Elsevier Inc., 2008)
    BACKGROUND - Non-alcoholic fatty liver disease (NAFLD) is increasing in the Asia-Pacific region.NAFLD can progress from simple steatosis, through steatohepatitis to advanced hepatic fibrosis, cirrhosis and hepatoma. Its ...
  • Epidemiology of paediatric constipation in Indonesia and its association with exposure to stressful life events 
    Oswari, H.; Alatas, F.S.; Hegar, B.; Cheng, W.; Pramadyani, A.; Benninga, M.A.; Rajindrajith, S. (Biomed Central, 2018)
    BACKGROUND: We aimed to study the epidemiology and risk factors, including exposure to emotional stress, for constipation in Indonesian children and adolescents of 10–17 year age group. METHODS: A cross-sectional survey ...
  • The epidemiology of soil-transmitted helminths in Bihar state, India. 
    Greenland, K.; Dixon, R.; Khan, S. A.; Gunawardena, K.; Kihara, J. H.; Smith, J. L.; Drake, L.; Makkar, P.; Raman, S.; Singh, S.; Kumar, S. (Public Library of Science, 2015)
    BACKGROUND: Soil-transmitted helminths (STHs) infect over a billion individuals worldwide. In India, 241 million children are estimated to need deworming to avert the negative consequences STH infections can have on child ...
  • Epidemiology of Stroke Subtypes and Aetiologies Among Sri Lankan Stroke Patients 
    Mettananda, K.C.D.; Eshani, M.D.P.; Wettasinghe, L.M.; Ranawaka, U.K. (Sri Lanka Medical Association, 2020)
    INTRODUCTION AND OBJECTIVES: Epidemiology of stroke subtypes in Asian countries is different from western countries. Data on stroke subtypes and aetiologies are limited from Sri Lanka. Therefore, we aimed to describe the ...
  • Epidemiology of stroke subtypes and aetiology among Sri Lankan stroke patients 
    Mettananda, C.; Wettasinghe, L,; Eshani, M.D.P.; Ranawaka, U. (Sage Publishing, 2020)
    BACKGROUND AND AIMS: Prevalence of stroke is on the rise in south Asia and the epidemiology is different to western countries. However, prevalence of stroke subtypes and aetiology is not reported of Sri Lanka. Therefore, ...
  • Epidermal naevus syndrome: 2 cases with a rare triad 
    Wanigasinghe, J.; Rodrigo, R.; Dissanayake, P. (Sri Lanka College of Paediatricians, 2013)
    No Abstract Available
  • Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study 
    Chambers, J.C.; Loh, M.; Lehne, B.; Drong, A.; Kriebel, J.; Motta, V.; Wahl, S.; Elliott., H.R; Rota, F.; Scott, W.R.; Zhang, W.; Tan, S.T.; Campanella, G.; Chadeau-Hyam, M.; Yengo, L.; Richmond, R.C.; Adamowicz-Brice, M.; Afzal, U.; Bozaoglu, K.; Mok, Z.Y.; Ng, H.K.; Pattou, F.; Prokisch, H.; Rozario, M.A.; Tarantini, L.; Abbott, J.; Ala-Korpela, M.; Albetti, B.; Ammerpohl, O.; Bertazzi, P.A.; Blancher, C.; Caiazzo, R.; Danesh, J.; Gaunt, T.R.; de Lusignan, S.; Gieger, C.; Illig, T.; Jha, S.; Jones, S.; Jowett, J.; Kangas, A.J.; Kasturiratne, A.; Kato, N.; Kotea, N.; Kowlessur, S.; Pitkäniemi, J.; Punjabi, P.; Saleheen, D.; Schafmayer, C.; Soininen, P.; Tai, E.S.; Thorand, B.; Tuomilehto, J.; Wickremasinghe, A.R.; Kyrtopoulos, S.A.; Aitman, T.J.; Herder, C.; Hampe, J.; Cauchi, S.; Relton, C.L.; Froguel, P.; Soong, R.; Vineis, P.; Jarvelin, M.R.; Scott, J.; Grallert, H.; Bollati, V.; Elliott, P.; McCarthy, M.I.; Kooner, J.S. J (The Lancet, Diabetes & Endocrinology, 2015)
    BACKGROUND: Indian Asians, who make up a quarter of the world's population, are at high risk of developing type 2 diabetes. We investigated whether DNA methylation is associated with future type 2 diabetes incidence in ...
  • Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity 
    Whal, S.; Drong, A.; Lehne, B.; Loh, M.; Scott, W.R.; Kunze, S.; Tsai, P.C.; Ried, J.S.; Zhang, W.; Yang, Y.; Tan, S.; Fiorito, G.; Franke, L.; Guarrera, S.; Kasela, S.; Kriebel, J.; Richmond, R.C.; Adamo, M.; Afzal, U.; Ala-Korpela, M.; Albeetti, B.; Ammerpohl, O.; Apperley, J.F.; Beekman, M.; Bertazzi, P.A.; Black, S.L.; Blancher, C.; Bonder, M.J.; Brosch, M.; Carstensen-Kirberg, M.; de Craen, A.J.; de Lusignan, S.; Dehghan, A.; Elkalaawy, M.; Fischer, K.; Franco, O.H.; Gaunt, T.R.; Hampe, J.; Hashemi, M.; Isaacs, A.; Jenkinson, A.; Jha, S.; Kato, N.; Krogh, V.; Laffan, M.; Meisinger, C.; Meitinger, T.; Mok, Z.Y.; Motta, V.; Ng, H.K.; Nikolakopoulou, Z.; Nteliopoulos, G.; Panico, S.; Pervjakova, N.; Prokisch, H.; Rathmann, W.; Roden, M.; Rota, F.; Rozario, M.A.; Sandling, J.K.; Schafmayer, C.; Schramm, K.; Siebert, R.; Slagboom, P.E.; Soininen, P.; Stolk, L.; Strauch, K.; Tai, E.S.; Tarantini, L.; Thorand, B.; Tigchelaar, E.F.; Tumino, R.; Uitterlinden, A.G.; van Duijn, C.; van Meurs, J.B.; Vineis, P.; Wickremasinghe, A.R.; Wijmenga, C.; Yang, T.P.; Yuan, W.; Zhernakova, A.; Batterham, R.L.; Smith, G.D.; Deloukas, P.; Heijmans, B.T.; Herder, C.; Hofman, A.; Lindgren, C.M.; Milani, L.; van der Harst, P.; Peters, A.; Illig, T.; Relton, C.L.; Waldenberger, M.; Järvelin, M.R.; Bollati, V.; Soong, R.; Spector, T.D.; Scott, J.; McCarthy, M.I.; Elliott, P.; Bell, J.T.; Matullo, G.; Gieger, C.; Kooner, J.S.; Grallert, H.; Chambers, J.C. (Nature Publishing Group, 2017)
    Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at risk of developing type 2 diabetes, cardiovascular disease and related metabolic and inflammatory disturbances. Although the ...
  • Epilepsy and outcome of pregnancy 
    Gunatilake, S.B.; Senanayake, A.E.S.; Mapa Pathirana, T.S.L.; Balasooriya, B.L.H.; Mettananda, K.C.D. (Sri Lanka Medical Association, 2005)
    BACKGROUND: Pregnancy in women with epilepsy is associated with increased obstetric risks and adverse fetal outcomes. OBJECTIVE: To study the effect of epilepsy and its treatment on pregnancy and the offspring. Methods: ...
  • Erectile dysfunction among male patients diagnosed with schizophrenia being treated with antipsychotic medication, and the impact on quality of life 
    Rowel, W. W. J. S. M .; Liyange, U. L. N. S.; Hewawitharana, U. H.; Dayabandara, M.; Rodrigo, A. (Sri Lanka College of Psychiatrists, 2018)
    INTRODUCTION:Erectile dysfunction is a distressing side effect of antipsychotics, which leads to poor medication compliance and poor quality of life. There is a scarcity of studies on antipsychotic-induced sexual dysfunction ...
  • Erythema induratum (of Bazin) in a patient with endometrial tuberculosis 
    de Silva, H.J.; Goonetilleke, A.K.; de Silva, N.R.; Amarasekera, L.R.; Jayawickrama, U.S. (BMJ Publishing Group, 1988)
    We report erythema induratum in a patient who was found to have active endometrial tuberculosis. This case report emphasizes the importance of an exhaustive search for active tuberculosis in patients with erythema induratum, ...
  • Erythrocyte antioxidant enzymes in patients with cataract 
    Chandrasena, L.G.; Chackrewarthy, S.; Perera, P.T.; de Silva, D. (Institute for Clinical Science., 2006)
    The pathogenesis of cataract has been found to be influenced by a number of factors including oxidative stress. Catalase, glutathione peroxidase (GPX), and superoxide dismutase (SOD) are some of the antioxidant enzymes ...
  • Esophageal motility, vagal function and gastroesophageal reflux in a cohort of adult asthmatics 
    Amarasiri, D.L.; Pathmeswaran, A.; Dassanayake, A.S.; de Silva, A.P.; Ranasinha, C.D.; de Silva, H.J. (BioMed Central, 2012)
    BACKGROUND: Asthmatics are known to have esophageal hypomotility. Vagal hypofunction and prolonged intra-esophageal acidification cause esophageal hypomotility. The contribution of gastroesophageal reflux (GER) and vagal ...

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