Young Ayurveda Researchers' and Innovators' Symposium
Permanent URI for this communityhttp://repository.kln.ac.lk/handle/123456789/20838
Browse
Item Analysis of the metal content in Ayurvedic medicated oil; Vāthavidurangādī thaila(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Jayasinghe, R.N.S.; Weerasooriya, W.M.B.; Rajapakshe, C.S.K.The Ayurvedic medicines of herbo-mineral origin are widely used in Sri Lanka. The metal contamination in such products is frequently reported in recent years. As accumulation of excessive amount of metals in the human body leads to various health hazards, the precise determination of such contaminants is required for safety assurance before usage. The Ayurvedic medicated oil, Vāthavidurangadī Thaila, is a popular medication prescribed by Ayurvedic physicians to treat several diseases and disorders. Therefore, this study was conducted to determine the concentration of selected metals in commercially available samples of Vāthavidurangadī Thaila using Atomic Absorption Spectrometry (AAS). The ten samples of Vāthavidurangadī Thaila collected from Colombo, Kandy, Kalutara, Galle and Gampaha districts were analyzed, for the content of Aluminum (Al), Copper (Cu), Cadmium (Cd), Chromium (Cr) and Lead (Pb) after acid digestion of samples with conc. HNO3 ,H2O2 and 70% HClO4. According to the results, Cu was found in all samples, Cr was detected in six samples but Pb was detected only in four samples. Al, Cu, Cd, Cr and Pb contents in oil samples were found in the range of 0.29-9.54 ppm, 2.34-10.80 ppm, 0.04-0.25 ppm, 3.02-4.39 ppm and 0.98-2.81 ppm respectively. The mean concentration values of Al, Cu, Cd, Cr and Pb were 4.7088 ppm, 4.7844 ppm, 0.0576 ppm, 1.5912 ppm and 0.8568 ppm respectively. The trend of abundance of metals in oil samples of Vāthavidurangadī Thaila followed the sequence of Cu >Al > Cr > Pb >Cd. According to the results, Al and Cr contents in some of the oil samples were higher than the maximum allowable limit recommended by WHO in drinking water. Chromium and Aluminum are not permissible for herbal medicines according to the WHO standards but Cd, Pb, Cu contents in all oil samples were lower than the maximum allowable limit recommended by WHO in herbal medicines.Item Antibacterial activity of Maha Thuwāla Thaila against laboratory specimens of Staphylococcus aureus: an experimental study(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Thiwanthika, U.A.C.; Vitharana, P.Ayurveda and indigenous herbal preparations are used in the treatment of various types of infectious wounds. They are composed of many herbs which naturally contain anti-microbial compounds. They can be effectively used against bacterial and fungal infections. Maha Thuwāla Thaila is a medicine for external application which is mostly used in indigenous medicine in Sri Lanka to cure chronic wounds, cut-injury wounds, orthopedic wounds and burned wounds. In addition, this oil preparation is clinically used in orthopedic treatment (Sandi Baghna Cikitsa) to cure Sandi Baghna. It consists of many herbs, oils, spices and minerals which have a number of anti-bacterial and anti-fungal compounds. Generally, all types of skin wounds are colonized by various types of bacteria. Common among these bacteria types is Staphylococcus aureus which is considered the classic opportunist bacteria which takes advantage of broken skin or other entry sites to cause an infection. But efficacy of this oil against Staphylococcus aureus in wounds is not scientifically evaluated. The purpose of this study was to evaluate tthe ant-bacterial activity of Maha Thuwāla Thaila against the laboratory specimen of Staphylococcus aureus by using Anti-bacterial Susceptibility Test (ABST). In this study Amoxicillin (5 mg/ml) was used as a positive control. The tested oil sample has shown 8.83 mm mean inhibitory zone diameter while positive control showed 39.33 mm of mean diameter. This result concludes that the tested samples of Maha Thuwāla Thaila showed less significant anti-bacterial activity against the laboratory specimens of Staphylococcus aureus bacteria under these laboratory conditionsItem A comparative study of Ayurveda and traditional treatment (Vedda community) modalities of snake bite in Sri Lanka(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Kumari, M.G.W.R.; Jayasinghe, J.M.P.R.K.Sri Lanka has one of the world’s highest death rates from snake bites. The current recommendation is to give anti-venom treatment only if the victim shows signs of envenoming and snake is highly venomous. Vedda people are the geography aborigines in Sri Lanka. They have their own treatment methods especially in snake bites. This study was conducted to identify the association between widely used common regimens among Vedda community and Ayurveda text to aid snake bite. The objectives were to compare Ayurveda and traditional treatment of snake bite in Sri Lanka, to identify the drugs used in the management of snake bites among indigenous people in Sri Lanka and to identify an immediate treatment for snake bite. Data were collected by a questionnaire, interview with the Vedda community and literary review. Veddas were selected from Dambana, Sri Lanka. Literary review was done by using only treatments which are mentioned in Carakasamhitha, Susruthasamhitha and Ashtangahridaya samhitha. According to the results obtained, there was evidence to confirm that the majority of medicinal plants mentioned in great treatise were used by Veddas. In addition to that some endemic plants are used by them for treatment of snake bite. Their main treatment is chewing bark of Gmelina asiatica (Demata). They used most common utterance for treatment of patient soon after a snake bite, whereas Ayurveda texts mentioned the same. Prepared drugs such as medicated oil, anti-poisonous stones are used by Vedda community. They do not have a long term management system due to their powerful emergency methodsItem Comparative study of the effect and efficacy of Sesame oil and Ghee on the blood lipid level(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Amarasinghe, K.A.I.; Dissanayake, K.G.C.In Ayurveda treatments there is a purification method name as purgation mainly aimed at reducing Pitta Dosha in which Dosha is expelled out through the anal passage. Before the purgation therapy Snehapana is done. Generally sesame oil and ghee oil are used in Snehapana. When applying oil internally, blood lipid level can be changed. Various researches have been already carried out on blood lipid level, yet there is a lacuna in the management of blood lipid level. Therefore, this study was undertaken to examine and compare sesame oil and ghee oil on the blood lipid level in the body after the purgation therapy. Hence in the present clinical study, 16 patients were selected and divided into 2 groups. The sesame oil was given to group A and ghee oil was given to group B. All the patients were investigated for total cholesterol level, HDL, Triglyceride, LDL, VLDL and total cholesterol / HDL ratio before and after treatment. According to data, when sesame oil was applied, patient’s total cholesterol, HDL, LDL mean value decreased but ghee oil applied patient’s mean values increased after the treatment. But triglyceride mean value increased after the treatment of both oils. But there was not a significant treatment effect. When considering the overall results of this study, according to the mean value sesame oil can be applied to increased blood lipid level patients but ghee cannot be usedItem Determination of metal content in Rasna Sapthaka Kwatha(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Abeysingha, W.A.M.U.S.; Nilmini, R.R.P.S.; Rajapakse, C.S.K.; Weerasooriya, W.M.B.Rasna sapthaka kwatha is a widely used Ayurvedic decoction. Medicinal plants that are the ingredients of this decoction are collected from different habitats of the country. The decoction can be contaminated with metals during the growing, collecting, and storing of the raw material and also during the processing of this product. Hence, the evaluation of metal concentration in pharmaceutically available decoction is of utmost significance. Therefore, the main objective of this research was to determine the concentration of Al, Cr, Cd, Cu, and Pb in decoction samples of Rasna sapthaka kwatha collected from different areas of Sri Lanka. Ten samples of decoction were randomly collected from Anuradhapura, Kurunegala, Kandy, Polonnaruwa, Thambuththegama, Galadiulwewa and Gampaha. Atomic Absorption Spectrometry was used to detect the metal concentration. Wet digestion was carried out prior to the analysis. The mean concentration value of Al, Cd, Cr and Cu were 1.010ppm, 0.232 ppm, 0.387 ppm and 0.155 ppm respectively. Pb was below the detected level of the instrument. Al, Cd, Cr and Cu contents in decoction samples were found in the range of 0.39-2.208 ppm, 0.18-0.348 ppm, 0.33-0.462 ppm, and 0.042-0.408 ppm respectively. Results revealed that the mean values of metal concentration of tested samples were below the recorded WHO permissible level of metals in herbal medicine.Item The effect of selected Yoga postures in the management of obesity and overweight with special reference to Body Mass Index(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Ekanayake, E.M.C.K.; Dissanayake, K.G.C.In world, more than half of adults and just below 20% children are overweight or obese. Yoga can improve strength and flexibility and may help control physiological variables such as blood pressure, lipids, respiration, heart rate and metabolic rate to improve overall exercise capacity. It is hypothesized that overweight and obesity can be managed by practicing selected Yoga. This study was focused on evaluation of the effects of yogic practice on overweight and obesity. Thirty overweight and obese patients were selected according to the inclusion and exclusion criteria from Gampaha Wickramarachchi Ayurveda Teaching Hospital. Body Mass Index, Waist hip ratio, Pulse rate, Skin fold thickness, Blood Pressure were estimated before the study. Overweight and obesity were assessed by using Body Mass Index (BMI). The patients were treated with seven types of Yoga asana, pranayama and meditation and prescribed dietary management during the period of 1 month. After the study, calculated p value for Body Mass Index is 0.00, which is less than 0.01. H0 was rejected at 1% significant level. Calculated p value for Waist hip ration is 0.00 which is less than 0.01. H0 was rejected at 1% significant level. Calculated p value for Pulse rate is 0.001, which is less than 0.01. H0 was rejected at 1% significant level. Calculated p value for Skin fold thickness is 0.00, which is less than 0.01. H0 was rejected at 1% significant level. Calculated p value for Systolic blood pressure is 0.01, which is equal to 0.01. H0 was rejected at 1% significant level. Calculated p value for Diastolic blood pressure is 0.01, which is equal to 0.01. H0 was rejected at 1% significant level. Therefore, there is a significant difference between above mentioned parameters before and after doing Yoga. Thus, the selected Yoga postures could be recommended in the management of overweight and obesityItem Effects of therapeutic purgation procedure on liver function and electrical activity of heart(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Gamage, H.P.Communicable diseases are a main health problem in the present world. Diseases of heart and liver are most common among them. Therefore, this study was conducted to determine the effect of therapeutic purgation on liver function and the electrical activity of the heart. Therapeutic purgation eliminates excessive vitiated dosha, mostly the Pitta dosha from the body through the anal route. After purgation, if there is a deformity in liver function or electrical activity of heart, it needs to be evaluated and the levels are to be compared before and after purgation therapy. In the present study, all the patients were selected from the IPD of Gampaha Wickramarachchi Ayurveda Hospital, Yakkala. Simple random sampling method was used to select the patients. 16 patients were selected according to the selection criteria. Before starting the treatment procedure liver function test report and electrocardiogram were taken from each patient. Deepana-Pachana drugs were given for 03 days and then the internal oleation started. Internal oleation continued for 05 days. Sedation was given in the evening of the last day of internal oleation and on the following day morning purgative drugs were given. After 02 days of proper purgation therapy, required tests were done. A follow up was done after one month of proper purgation. The patients showed significant reduction in liver function tests (SGOT, SGPT and Serum bilirubin). But in this study, significant changes of electrical activity of the heart were not presented. Thus, the therapeutic purgation could be recommended for the management of liver diseases, specially for fatty liver when purgation is appropriateItem Effects of therapeutic purgation procedure on renal function and serum electrolytes level(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Alagiyawanna, A.M.A.N.N.; Dissanayake, K.G.C.Therapeutic purgation is one among the Panchakarma therapies, which eliminates excessive vitiated Dosha mostly the Pitta Dosha from the body through the anal route. Under normal circumstances, if a patient suffers from diarrhea, there is certainly the loss of electrolytes from the body resulting in weakness, development of cramps due to dehydration and sometimes low blood pressure and renal failure. However, if purgation is induced through Virechana therapy and if features of proper Virechana occur, no such symptoms will occur. After purgation, if there is an electrolyte imbalance or deformity in renal function, it needs to be evaluated and the levels are to be compared before and after Virechana therapy. The present study was designed to determine the effect of therapeutic purgation procedure on renal function and serum electrolytes level. All the patients were selected from the IPD of Gampaha Wickramarachchi Ayurveda Hospital, Yakkala. Simple random sampling method was used to select the patients. 16 patients were selected according to the selection criteria. Before starting the treatment procedure Renal function test report and Serum electrolytes level report were taken from testing a blood sample of each patient. Deepana pachana drugs were given for 03 days and then the internal oleation started. Internal oleation continued for 05 days. Sudation was given in the evening of last day of internal oleation and morning and evening of the following day. Pitta uthkleshaka diet was given as the dinner. The following morning purgative drugs were given. After 02 days of proper purgation therapy required tests were done. A follow up was done after one month. Research group resulted significant change in blood urea, serum creatinine levels and serum electrolytes levels. Thus, the purgation therapy has a significant effect on renal function and serum electrolytes levelsItem Efficacy of a prepared traditional lepa for the management of Amavata sandi shotha(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Prabash, K.G.D.; Wickramarachchi, W.J.Amavata is a disease caused by vitiation of Vata by Ama, which is the product of incomplete digestion and metabolism. Agni in Ayurveda includes the digestive processes of gastrointestinal tract as well as the metabolic processes in tissues. Ama could therefore be produced by flawed digestion in gastrointestinal tract or in the tissues by defective metabolic process. Ama thus produced is said to circulate and block the vessel of the joints and get deposited there causing inflammation by producing symptoms such as pain, moving discomfort, swelling and morning stiffness in small and big joints, making a person lame. Various drug trails were already carried out on Amavata, yet there is a lacuna in the management of Ama vata. Therefore this study was undertaken to examine the efficacy of a prepared traditional lepa in the management of Amavata sandi shotha. Hence, in the present clinical study, 30 patients were selected and divided into 2 groups, Group A and B. Group A was given Sarshapa oil and group B the test group was given, traditional lepa. The collected data was recorded according to the age, sex and a paired sample t – test was applied for the clinical assessment of the subjective parameters. During treatment no side effects were noted. According to the analysis all P- values of the test group in the comparison of before and after treatment in full duration were less than 0.05 (P - values before and after treatment on pain (0.000), moving discomfort (0. 000), edema (0. 000), redness (0.012), burning sensation (0.000), ESR (0.010) and Rheumatoid Factor 0.025). The results obtained were significant statistically in traditional lepa. Therefore, the study confirms that the traditional lepa is effective in the management of Amavata sandishothaItem Efficacy of Ayurvedic formula mentioned in Susrutasamhitha in the management of Kalithya(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Dharshika, A.K.D.; Wickramarachchi, W.J.Hair loss becomes one of the common problems in society. Falling hair is one of the diseases of head region, known as “Kalithya” in Ayurveda. There are varieties of reasons for hair loss, including autoimmune diseases, stress, poor nutrition, some medications, mineral deficiency, pollution, severe illness, excessive styling, pregnancy, hereditary and even poor hair care, while wearing helmets and caps can also increase the risk of hair loss. Today more and more people are turning toward the Ayurveda to find a solution for hair loss. Ayurveda believes that hair fall control is very much associated with the body type and also the stability of both body and mind structure of the person. To overcome Kalithya there are many treatments modalities described in Ayurveda texts, like Shirolepa, Shiroabyanga, Shirodhara, Shirovasthi etc. In this study, shirolepa was considered as the treatment modality. Application of medicated paste on the scalp is known as Shirolepa. Most of the shiro lepa are not scientifically evaluated. This formula is one of them mentioned in Susrutasamhitha. Equal quantities of Karanda (Pongamia pinnata) leaves, juice of Kapitta (Limonia acidissima L.) and Kasisa purified using Bhrungaraja (Eclipta alba) decoction were used to make the herbal paste. In the clinical study 20 patients were selected in age between 20-50 years, irrespective of their religion, occupation and habits. They were randomly divided in to two groups. Group A was treated with shiro lepa and group B was treated with Brungamalaka Thaila (traditional effective Thaila for scalp). All of them completed the treatments accurately and the follow up study continued up to one month after treatments. After considering the results, it can be concluded that herbal paste is more effective in fallen hair, itching condition, hair dandruff and hair color except regrowth of the hairItem Ethno-botanical survey on “Wellangiriya”(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Geethapriya, R.H.S.M.; Wanigasekara, M.M.G.N.C.; Mudiyanse, P.M.T.D.; Gujeenton, R.; Suranga, P.; Rangana, N.Many people in developing countries still rely on traditional healing practices and medicinal plant for their health care need. In Sri Lanka, medical practitioners use Wellangiriya plants for their treatments. Wellangiriya plant is used in medicinal preparations in Ayurveda and Deshiya Cikitsa such as Winaraja Kayama, Sathwawadi oil, Sarwawishadi oil etc. But there are some varieties of Wellangiriya. Therefore, ethno-botanical survey of ‘’Wellangiriya’’ is essential for the society. A questionnaire was prepared to be distributed among Ayurveda medical practitioners of the Western Province, Southern Province & Sabaragamuwa Province for collecting details such as, Capparis zeylanica, Capparis mooni and Pereskia aculeata used for Wellangiriya by the medical Practitioners. According to the results they use 2 plant species for Wellangiriya in Capparacae family. Pereskia aculeata is an introduced plant for Sri Lanka. Mainly 3 varieties of plants are used for Wellangiriya. They are Capparis mooni, Capparis zeylanica and Pereskia aculeata. It varies from the areas. Most commonly used variety for the medicinal preparations and treatments is Capparis zeylanicaItem Evaluation of effects of herbal formula mentioned in “Aushada Samgraha” in the management of Suryavartha(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) De Silva, W.C.S.Suryavartha is the commonest clinical condition which is directly related with the position of the sun in the sky. The symptomatology of Suryavartha reveals its close resemblance with that of frontal sinusitis. This study aimed at finding the efficacy of a herbal formula oil including Dashamoola, thila thaila and Cow’s milk. Assessment of the effect of treatment was done on the basis of relief of those subjective and objective parameters of Suryavartha under a grading system. Twenty four patients had engaged in this study and eight patients were instructed to use herbal formula oil and another eight patients were given internal medicine and the others were given both research oil and internal medicine. Observations were recorded after one month. According to SPSS data analyzed P value in the comparison between before and after treatment of Group A, B and C, for all parameters P values were less than 0.05 of Group A and B. But in group C, P value is less than 0.05 only for headache and nasal discharge before and after treatments. According to the clinical study in all groups there is an improvement of reducing the symptoms after 4 weeks of treatment period. But there is a marked improvement of reducing symptoms in the group which was given both research oil and internal medicine. The improvement of reducing symptoms in the group which was given research oil is better than the group which was given only internal medicine. It can be concluded that herbal formula is more effective with the internal medicine in the management of Suryavartha.Item Evaluation of the anti-bacterial effect of traditional Lodhradi lepa and Lodhradi cream against the laboratory specimen of staphylococcus aureus: a laboratory experiment(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Madushani, P.A.K.; Wickramarachchi, W.J.Acne vulgaris is a chronic disease which destroys the beauty and cause disfigurement of the face especially in the adolescence. Acne vulgaris is known as Mukhadushika or Yuvana Pidaka in Ayurveda. Acne vulgaris, secondary infected by Staphylococcus aureus. Lodhradi lepa is an external application for Yuvana Pidaka in Ayurveda. The study was to test the anti-bacterial activity of the traditional Lodhradi lepa and Lodhradi cream against the Staphylococcus aureus. The anti-bacterial sensitivity test was done on well diffusion method with freshly prepared drugs. In trial one it was tested with freshly prepared drugs and the second trial was done with two different concentrations of freshly prepared drugs. In both trials the zone diameters were among 00-12mm and as the diameters were not among the resistant or susceptible level Staphylococcus aureus is not susceptible to these external ointments. Erythromycin the positive one was highly susceptible. Staphylococcus aureus was not susceptible for the traditional Lodhradi lepa and Lodhradi cream. The traditional Lodhradi lepa and Lodhradi cream would be used in acne vulgaris to reduce inflammation like symptoms due to its pacifying properties.Item Evaluation of the antibacterial effect of Acronychia pedunculata fresh extract against Staphylococcus aureus: a study in vitro(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Muthukuda, M.A.C.LIn vitro antibacterial activity of fresh extracts of stem bark, leaves and combined sample of Acronychia pedunculata found in Sri Lanka were investigated against Staphylococcus aureus (ATCC 25923) and found the Minimum Inhibitory Concentration. Kirby Baurer Well diffusion method of antibacterial Susceptibility Testing was used to determine antibacterial activity of each fresh extract. Dilution series for Minimum Inhibitory Concentration were prepared. Amoxacillin and distilled water were used as positive and negative control respectively. Zone diameters were interpreted and data were statistically analyzed. The results showed that there was antibacterial effect of each sample. The highest zone diameter was observed for the combined sample; fresh extracts of stem bark and leaves (11.67mm). This could be due to the synergetic activity of each compound from each plant material used in this study. Fresh extracts of stem bark showed the second most (11mm) and fresh extracts of leaves the least (9mm). As fresh extracts of stem bark and leaves of Acronychia pedunculata (combined sample) showed the highest activity, dilution series from that sample were prepared. The minimum inhibitory concentration of combined sample for the growth of Staphylococcus aureus was 10-2 mg/ml. This could be further investigated for more gram positive and negative bacterial and fungal species. It is worth to investigate each extract individually using various chromatographic techniques and identify the active ingredients separately.Item Evaluation of the clinical efficacy of Śāriwothphalādi lepa in the management of migraine(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Vithana, V.K.V.N.; Kasthurirathna, K.T.S.C.Headaches are classified as primary and secondary. Migraine is the most common of primary headache disorders. Migraine disorders are further classified into migraine without aura, migraine with aura, familial or sporadic hemiplegic migraine, and basilar-type migraine. Complications of migraines include chronic migraine, status migrainous, persistent aura without infarction, migrainous infarction, and migraine-triggered seizures. Migraine has different symptoms; it may be different from person to person. This study aimed at finding the efficacy of an herbal formula lepa including Hemidesmus indicus, Nymphaea lotus L., Saussurea lappa, Glycyrrhiza glabra L. which was a safe and effective external mode of therapy for migraine without side effects. Throbbing, pulsating pain, photophobia, phonophobia, nausea & vomiting, visual disturbance, tinnitus and duration of headache were assessment criteria & assessment of the effect of treatment was done on the basis of relief of the subjective and objective parameters of migraine under a grading system. Thirty patients had engaged in this study. All were advised to avoid the other treatments for migraine & apply the lepa on pained area, when they feel migraine. Observations were recorded after six months. While considering the P value of symptoms, P value <0.05 for throbbing, pulsating pain, photophobia, phonophobia, visual disturbance, duration of headache. So Śariwothphaladi lepa is effective on these five symptoms. But P value>0.05 for nausea and vomiting, tinnitus. So it is not effective on these two symptoms. According to pharmacodynamics action, it has Pitta shamaka and Kapha wardaka property. So it has deep sleepy condition after using Śariwothphaladi lepa. It is helpful to reduce symptoms of migraine quickly. According to the study Śariwothphaladi lepa has given effect for reducing the symptoms of migraine. Finally, it was confirmed that Śariwothphaladi lepa is effective in the management of migraine.Item Evaluation of the clinical efficacy of Varshaabu Lepa in the management of Uththana Vata Rakta(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Jeeewanthi, J.A.H.; Vitharana, P.Vatha Rakta is a variety of Vata Roga which shows a high prevalence in the world and caused by vitiation of both Vata and Rakta. When the process of Margavarana takes place in the “Rakta Marga” due to the abnormal and excessive accumulation of morbid Kapha and medas in the srotas, it ends up in the manifestation of Vata Rakta. It is two varieties, Uththana (superficial) and Gambheera (deep seated). The superficial variety of Vata Rakta gives rise to itching, burning sensation, expansion, pricking pain, contraction and brownish black red or copper colour in the skin. This study was aimed at finding the efficacy of an herbal formula Lepa including Hordeum vulgare, Glycyrrhza glabra Linn, Rinus commiunis, Sesamum indicum, Boeraria diffusa Linn., which was safe and effective external mode of the therapy for Uththana Vata Rakta without side effects. Pain, burning sensation, itching, oedema, local colour changes in the skin and walking ability are assessment criteria and assessment of the effect of treatment was done on the basis of relief of that subjective and objective parameters of Utththana Vata Rakta under a grading system. Thirty patients had participated for this study and patients were instructed to use herbal formula Lepa. Patients were selected randomly irrespective of their sex, religion, occupation and habitat. Patients were within the age group of 20 -70 years and presenting with Pratyatmaka Lakshana of Uththana Vata Rakta. All were advised to avoid the other treatment for Vata Rakta. Observations were recorded after one month. While considering the p value of Test group, p value < 0.05 for Pain, burning sensation, itching, oedema, local colour changes in the skin and walking ability. So According to the study, herbal formula Lepa has given a marked effect for reducing the symptoms of Uththana Vata RaktaItem Evaluation of the deodorant action of Nagakesara(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Hazari, F.S.; Jayasinghe, J.M.P.R.K.Sweating is a natural process that our body goes through each and every day. The purpose of sweating is to cool the body down and remove toxins. But heavy sweating causes problems or distress. It is caused by spicy foods, hard works, caffeine, mental issues and hereditary. Because of the above etiological factors, the body temperature rises and the sympathetic nerve stimulates the sweat glands to produce excessive secretion which leads to clinical manifestations like disruption of normal activities, wet palms, hands, arm pits, frequent sweating, noticeable sweating that soaks that we clothing, skin problems, stained cloths and body odor. A clinical study was designed to evaluate the deodorant action of Nagakeshara (mesuaferrea). The study was carried out on 60 patients of both sexes between 16 - 40 years with complaints of frequent sweating, noticeable sweating that soaks to the cloths, odor formation and color change in axillary region. Two groups were selected and the test group was used to test the deodorant action of the Nagakeshara and ghee (Lepa A). Control group was used to test the action of the ghee (Lepa B). The study was carried out for 21 days. According to the results in present study, it could be concluded that short term administration of the drug has shown significant effect decreasing the severity of the disease.Item Evaluation of the effect and efficacy of herbal powder preparation derived from ‘Thalpathe Piliyam’ in the management of type II Diabetes mellitus(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Harshamali, K.A.D.T.; Sakunthala, H.S.Diabetes Mellitus is a metabolic disorder of multiple etiology characterized by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action or both. The effects of Diabetes Mellitus include long-term damage, dysfunction and failure of various organs (WHO, 1999). It is a chronic disease caused by inherited and acquired deficiency in production of insulin by the pancreas or by the ineffectiveness of the insulin produced. Such a deficiency results in increased concentrations of glucose in the blood, which in turn damage many of the body’s systems, especially the blood vessels and nerves. (WHO, 2013) This study was designed to determine the effect and efficacy of selected herbal formulation mentioned in “Thalpathe Piliyam” in the management of type II Diabetes. All patients were selected from medical clinic of Gampaha Wickramarachchi Ayurveda Teaching Hospital according to the inclusion and exclusion criteria. The selected patients were assigned into two groups (group A and B) consisting of 30 patients for each group. The patients of group A were treated with the powder of selected herbal formula and dietary management during the period of 1 month. Patients of group B were treated with allopathic medicine and dietary management during the period of 1 month. After 1 month, the patients of group A and group B showed significant reduction in fasting blood sugar and blood pressure and heart rate. Thus, the powder of selected formulation could be recommended in the management of type II DiabetesItem Evaluation of the effect of herbal formula mentioned in Bhaisajya Rathnavali in the management of Pityriasis versicolor(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Dissanayake, A.M.S.H.; Jayakody, J.A.D.P.P.Tinea versicolor is a frequent benign superficial fungal infection of the skin. It belongs to Malassezia related disease. Clinical features of Tinea versicolor include either hyperpigmented or hypopigmented finely scaly macules. The most frequently affected sites are the trunk, neck and proximal extremities. However, long term maintenances of treatment is often required due to its high recurrence rate. Tinea versicolar is generally asymptomatic although some patients experience mild pruritus. This study was designed to assess the effect and efficacy of an herbal formula cream including Saussurea lappa, Raphanus sativus, Brassica juncea, Curcuma longa, Mesua ferrea, Callicarpa macrophylla Vah and cow’s urine which was a safe and effective external therapy for Pityriasis versicolor. This study assessed on the distribution pattern in relation to age, gender, affected region, occupations and chronicity among Tinea versicolor patients. Also size, colour, clinical form and itching of the affected area were assessed and effect of the treatment was measured through a well-defined grading system in term of selected reliving parameters. Thirty patients participated in the study, who were randomly divided in to two groups as group A and B. Group A was given herbal formula cream and Group B was given Charmakathi lepa. Patients were advised to refrain from any other treatment for Tinea versicolar. Follow up period was four weeks. When considering the P values, test group P value for size, colour, itching and clinical form were < 0.05. In control group, P value < 0.05 for itching and P value > 0.05 for size and colour and clinical form. Therefore, it can be concluded that herbal formula cream is more effective than Charmakanthi lepa in the management of Tinea versicolarItem Evaluation of the effect of Spatikadi Prathisarana in the management of Sheetada(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Balasooriya, B.P.L.R.Sheetada is one of the dantha moolagatha roga mentioned in Susruthasamhitha under the headings of Mukha roga. It occurs due to vitiation of Kapha Raktha. In modern medicine Sheetada can be correlated with marginal gingivitis on the basis of similarities of symptoms. Marginal gingivitis occurs widely in most populations, affecting both children and adults. The epidemiological studies conducted by American Academy of Periodontology shows that gingivitis of varying severities is nearly universal. It is estimated that over 80% of the world's population suffers from gingivitis. This study was carried out to evaluate the effectiveness of Spatikadi Prathisarana mentioned in Rajaushadasaraya in the management of Sheetada. 30 patients were selected with written consent from Shalakya OPD at Gampaha Wickramarachchi Ayurveda Teaching Hospital by using a proforma. They were randomly divided into two groups; group A and B irrespective of their sex, age, habitat ect. In group A-Spatikadi Prathisarana local application on gums and in group B, Triphala choorna on gums was given. After the enrollment of the patients clinical features of Sheetada such as Rakthsrawa, Krishnatha, Shotha, Mukha Dauragandya, Mrudutha, Prakledatha were studied and also objective criteria such as Gingival index (GI-S), and Gingival bleeding index (GBI-S) were studied before and after treatment. Rakthasrawa, Krishnatha, Shotha, Mukha Dauragandya, Dantha mansa mrudutha were statistically more significant in Group A than group B. Objective parameters such as GI-S and GBI-S also showed statistically significant results in both groups. Observation in follow-up study confirmed that the recurrence rate in the group A was significantly lesser than group B.