Chemistry
Permanent URI for this collectionhttp://repository.kln.ac.lk/handle/123456789/3748
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Item Two new bioactive poliketides from Culvularia trifolii, an endolichenic fungus isolated from Usnea sp., in Sri Lanka(2015) Samanthi, K.A.U.; Wickramarachchi, S.; Wijeratne, E.M.K.; Paranagama, P.A.Item Two new antioxidant active polyketides from Penicillium citrinum, an endolichenic fungus isolated from Parmotrema species in Sri Lanka(National Science Foundation of Sri Lanka, 2015) Samanthi, K.A.U.; Wickramaarachchi, S.; Wijeratne, E.M.K.; Paranagama, P.A.Bioassay guided fractionation of the ethyl acetate extract of a laboratory culture of Penicillium citrinum, an endolichenic fungal strain isolated from a Parmotrema species in Sri Lanka, led to the isolation of two new fungal polyketides (1 and 2). The structures of these compounds were determined on the basis of their 1D NMR, 2D NMR and FABMS spectroscopic data. The two compounds (1 and 2) showed radical scavenging activity with IC50 values of 159.7 ± 22.3 μg/mL and 68.6 ± 4.3 μg/mL, respectively in DPPH antioxidant assay. The antioxidant activity of compound 2 was comparable to the standard antioxidant compound butylated hydroxytoluene (BHT).Item Sesquiterpene Quinones and Related Metabolites from Phyllostictaspinarum, A Fungal Strain Endophytic in Platycladusorientalisof the Sonoran Desert(J. Nat. Prod, 2008) Wijeratne, E.M.K.; Paranagama, P.A.; Burns, A.M.; Marron, T.; Gunatilaka, M.K.; Arnold, A.E.; Gunatilaka, A.A.L.Item Accessing plant-associated microbial diversity for discovery of small molecule bioactive agents(Accessing plant-associated microbial diversity for discovery of small molecule bioactive agents, 40th IPUAC Congress, 2005) Wijeratne, E.M.K.; Turbyville, T.J.; Bashyal, B.P.; Zhan, J.; Jian, H.; Paranagama, P.A.; Seliga, C.J.; Liu, M.X.; Burns, A.M.; Whitesell, L.; Gunatilaka, A.A.L.Gunatilaka, A.A.L.Item Effect of metal ions on polyketide biosynthesis in Paraphaeosphaeria quadriseptata(Proceedings of the 19th Rocky Mountain Regional Meeting, American Chemical Society, 2006) Paranagama, P.A.; Wijeratne, E.M.K.; Gunathilaka, A.A.L.Item Discovery of small molecule bioactive agents from endophytic fungi of the Sonoran Desert(New Zealand Grassland Association: Endophyte Symposium, 2007) Bashyal, B.P.; Burns, A.M.; Liu, M.X.; Paranagama, P.A.; Seliga, C.J.; Turbyville, T.J.; Wijeratne, E.M.K.; Zhan, J.; Gunathilaka, M.K.; Arnold, A.E.; Faeth, S.H.; Whittesell, L.; Gunathilaka, A.A.L.Item Five new isocoumarins from Sonoran desert plant-associated fungal strains Paraphaeosphaeria quadriseptata and Chaetomium chiversii(Tetrahedron, 2006) Wijeratne, E.M.K.; Paranagama, P.A.; Gunatilaka, A.A.L.Item Heptaketides from Corynespora sp. Inhabiting the Cavern Beard Lichen, Usnea caWernosa: First Report of Metabolites of an Endolichenic Fungus(J. Nat. Prod., 2007) Paranagama, P.A.; Wijeratne, E.M.K.; Burns, A.M.; Marron, T.; Gunatilaka, M.K.; Arnold, A.E.; Gunatilaka, A.A.L.Priyani A. Paranagama,?,? E. M. Kithsiri ,? Anna M. ,? Marilyn T. ,? Malkanthi K. ,? A. Elizabeth ,? and A. A. Leslie *,?Item Uncovering Biosynthetic Potential of Plant-Associated Fungi: Effect of Culture Conditions on Metabolite Production by Paraphaeosphaeria quadriseptata and Chaetomium chiWersii(J. Nat. Prod., 2009) Paranagama, P.A.; Wijeratne, E.M.K.; Gunatilaka, A.A.L.Priyani A. gama,? E. M. Kithsiri , and A. A. Leslie *