Browsing by Author "Rodrigo, K.M.D.J."

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    Marked eosinophilia due to intestinal strongyloidiasis in an immunocompetent patient
    (Sri Lanka Medical Association, 2012) Rodrigo, K.M.D.J.; Premaratna, R.; Chandrasena, T.G.A.N.; de Silva, N.; de Silva, H.J.
    Strongyloides stercoralis is unique among the intestinal nematodes in that it has a free-living cycle in warm and tropical climates in addition to a parasitic cycle in its human host. In immuno-competent hosts, this parasite is mostly confined to the intestinal tract. Infection may be asymptomatic or it may induce a wide variety of symptoms such as nausea, vomiting, abdominal pain, chronic diarrhea, loss of weight and pruritus of the perianal region caused by autoinfective larvae ('larva currens'). Although intestinal nematode infections are relatively common in Sri Lanka, infection with S. stercoralis is infrequently reported. Prevalence rates of S. stercoralis infection in Sri Lanka range from 0-1.6% [1,2,3]. Here we report a case of symptomatic intestinal strongyloidiasis with marked eosinophilia.
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    Repeated dengue shock syndrome and 'dengue myocarditis' responding dramatically to a single dose of methyl prednisolone
    (Elsevier(Open Access), 2012) Premaratna, R.; Rodrigo, K.M.D.J.; Anuratha, A.; de Alwis, V.K.D.; Perera, U.D.C.A.; de Silva, H.J.
    The place of steroids in the management of severe forms of dengue is unclear. A retrospective observational study showed the benefits of a single dose of intravenous methyl prednisolone in a highly selected group of patients who developed severe dengue during the febrile phase of infection. We report the case of a 14-year-old boy with dengue who developed three episodes of severe hemodynamic compromise while having high fever, 'myocarditis', third space fluid accumulation, progressive reduction in urine output, and altered mentation, who made a dramatic recovery following a single dose of intravenous methyl prednisolone. Results justify a well powered randomized controlled trial to evaluate the efficacy of this treatment in severe dengue.