Browsing by Author "Pushpakumara, A.A.J."

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Anti-bacterial Activity of different extract of Curcuma longa in the management of Fistula in ano
(European Journal of Biomedical and Pharmaceutical Sciences, 2017) Pushpakumara, A.A.J.; Jayaratne, D.L; Samaranayake, G.V.P.
Ayurvedic parasurgieal treatment procedure Ksharasutra was one of the effective treatment for management of the fistula in ano. Curcuma longa was the one of the main ingredient in a thread. In the present work an attempt hæ; been made to analyn the antibacterial and potential of methanol, ethanol and aqueous extracts of Curcuma longa against E coli S. aureug, Sagalactiae and P_aeruginosa among bacterial strains by disc diffusion method and the antibacterial were determined by masuring the diameter of mne of inhibition. The reports on extraction method using soxhlet extractor The methanol extracts of Curcuma longa p»ssessed the highest antibacterial with a zone of inhibition of 34 mm for, S aureus and lowest 13mm for P. aeruginosa, ethanol extract has range of Of inhibition 3 1 mm-IOmm while lowest antibacterial activities was reported alueous extract range 28mm-l I mm zone Of inhibition
An Ayurvedic Appraoch in the management of Ashmari (Urolithiasis)
(International Journal of Current Innovations in Advanced Research, 2019) Samaranayake, G.V.P.; Peiris, K.P.P.; Pushpakumara, A.A.J.
In ancient centuries urolithiasis was often a disease, with a catastrophic outcome all too often leading to the patient's death. Even today, urolithiasis is the one of the most common affliction of the urinary tract. Detailed medical literature on urolithiasis is available from ancient India. As per classics, Ashmari is included in Ashtamahagada due to its fatal nature. Description of Ashmari is found in almost all Samhita Of Ayurveda as etiopathogenesis, classification, symptomatology, complications and management in a most scientific manner- Modem science also emphasizes on involvement of various factors like heredity, age, sex, metabolic disorders, hydration status, mineral content of water, nutritional deficiency, etc. For urinary stone formation. Urolithiasis typically occurs in middle age which is the most productive years of life. It causes pain, loss of working time, medical expenses, needs for hospitalization as well as it is infrequent cause of renal failure and death. Different management of urolithiasis has been developed in modern system but inspite of all these techniques, surgery remain treatment of choice. Even after surgery patients have to take medicines to check its further recurrence. In this way the need of medicinal treatment is always required.
An Ayurvedic Appraoch in the management of Ashmari (Urolithiasis)
(International Journal of Current Innovations in Advanced Research, 2019) Samaranayake, G.V.P.; Peiris, K.P.P.; Pushpakumara, A.A.J.
In ancient centuries urolithiasis was often a disease, with a catastrophic outcome all too often leading to the patient's death. Even today, urolithiasis is the one of the most common affliction of the urinary tract. Detailed medical literature on urolithiasis is available from ancient India. As per classics, Ashmari is included in Ashtamahagada due to its fatal nature. Description of Ashmari is found in almost all Samhita Of Ayurveda as etiopathogenesis, classification, symptomatology, complications and management in a most scientific manner- Modem science also emphasizes on involvement of various factors like heredity, age, sex, metabolic disorders, hydration status, mineral content of water, nutritional deficiency, etc. For urinary stone formation. Urolithiasis typically occurs in middle age which is the most productive years of life. It causes pain, loss of working time, medical expenses, needs for hospitalization as well as it is infrequent cause of renal failure and death. Different management of urolithiasis has been developed in modern system but inspite of all these techniques, surgery remain treatment of choice. Even after surgery patients have to take medicines to check its further recurrence. In this way the need of medicinal treatment is always required.
An Ayurvedic Approach in the Management of Urolithiasis
(International Journal of Current Innovations in Advanced Research, 2019) Samaranayake, G.V.P.; Peiris, K.P.P; Pushpakumara, A.A.J.
In ancient centuries urolithiasis was Often a disease, with a catastrophic outcome all too often leading to the patient's death. Even today, urolithiasis is the one of the most common affliction of the urinary tract. Detailed medical literature on urolithiasis is available from ancient India. As per classics, Ashmari is included in Ashtamahagada due to its fatal nature. Description Of Ashmari is found in almost all Samhita Of Ayurveda as etiopathogenesis, classification, complications and management in a most scientific manner. Modern science also emphasizes on involvement of various factors like heredity, age, sex, metabolic disorders, hydration status, mineral content of water, nutritional deficiency, etc. For urinary stone formation. Urolithiasis typically occurs in middle age which is the most productive years of life. It causes pain, loss of working time, medical expenses, needs for hospitalization as well as it is infrequent cause of renal failure and death. Different management of urolithiasis has been developed in modern system but inspite of ail these techniques, surgery remain treatment Of choice. Even after surgery patients have to take medicines to cheek its further recurrence. In this way the need of medicinal treatment is always required.
Ayurvedic Management of Benign Prostate Hypertrophy
(S. Godage and Brothers (Pvt) Ltd, 675, P. de S. Kularatne Mw., Colombo 10, Sri Lanka, 2014) Pushpakumara, A.A.J.
Ayurvedic Management of Heamorrhoids
(S. Godage and Brothers (Pvt) Ltd, 675, P. de S. Kularatne Mw., Colombo 10, Sri Lanka, 2014) Pushpakumara, A.A.J.
Case Study Of Leech Application In Varicose Ulcer
(International Journal of Scientific & Technology Research, 2016) Samaranayake, G.V.P.; Pushpakumara, A.A.J.; Waliwita, W.A.L.C.
Varicose ulcers are wounds that are thought to due to impropr fundioning of venous valves, usually of the legs. They are the major occurrence of chronic wounds, occurring in 70% to 90% of leg ulcer cases. In Sushrut Samhita, where get the most scientific description of wound and its management Similarly, Sushrut has given the almost importance to Bloodletting therapy and considered leech as the most unique and effective method of bloodletting even in infected wounds and abscesses. Aforesaid description let us to try leech therapy in venous ulcer was advised to continue weekly application of leech around the ulcer which was followed by dressing with Seethodaka oil and Dashanga lepa. This leech therapy proved very effective and the ulcer healed completely within 30 days. However further evaluation is required to done by taking a large samples size to prove is' treating Venous ulcer
A Case Study of observe the effect of unripe Carica papaya pulp in improving the Blood Circulation around Chronic Wound
(1st International Conference and Exhibition in Indigenous Medicine – ICEIM – 2018, Organized by Indigenous Medicine, Eastern Province with the collaboration of Unit of Siddha Medicine, Trincomalee Campus, Eastern University of Sri Lanka, 2018) Samaranayake, G.V.P.; Pushpakumara, A.A.J.
A chronic wound ig a wound has does not heal in an orderly set Of Stages and in predictable amount of time the Way. poor blood circulation is one Of the major factors which hinder wound healing leading to chronic ulcers. Accumulation of deoxygenated blood around the wound is responsible for giving rise to blackening of the skin, itching and low temperature around the wound while decelerating the healing process. The pulp of the unripe Carica papaya fruit is traditionally used as a paste around the chronic wound as an aid to improve the skin condition. This study was conducted to observe i*effect on circulation improvement taking two cardinal signs of poor blood circulation which are discoloration of skin and itching as indicators. This study was conducted at Shalya Clinic Of Gampaha Wickramarachchi Ayurveda Hospital. A _ 54 years old female patient presented with a non-healing wound in dorsum of the left lower limb for 2 years. First cleaned the wound by using Pancha walkala quatha and applied a paste Of the pulp of unripe Carica papaya fruit mixed with bee's honey around the wound. Treatment was carried out for 6 weeks. The results were recorded weekly using a scoring system based on the severity of symptoms. At the end of the period the patient was relieved of itching considerably, replaced the wound base with healthy granulation tissues and showed an improvement of skin color around the wound. Reduction of these symptoms could be taken as indications of an improving blood circulation around the affected area. In this study, it was seen that Carica papaya pulp applied around wounds which are positive for the above 3 symptoms were successful in reducing discoloration, itching and increasing healthy granulation tissues. Therefore, it was concluded that the pulp of unripe Carica papaya has the ability to improve the circulation around chronic wound.
Case study on Kshara Application in Diabetes foot ulcer
(5th International Conference on Ayurveda, Unani, Siddha & Traditional Medicine 2017 (ICAUST 2017)-Ayurveda organized by Institute of Indigenous Medicine, University of Colombo, Rajagiriya, Sri Lanka, 2017) Samaranayake, G.V.P.; Pushpakumara, A.A.J.
Diabetes foot ulcer are a consequence of many factors including loss of protective sensation due to peripheral neuropathy when the feet become numb and the injury goes unnoticed. Also arterial insufficiency complicates the neuropathic ulcer which leads to poor wound healing. Infection further deteriorates the diabetic foot resulting in a non- healing chronic wound. The primary goal in the treatment of diabetes foot ulcer is to obtain wound closure. Main stay of treatment includes antibiotics, detriments and local wound and foot wear improvisation. In spite of all advances in health sciences. Statistic reveals that about 3% patients yet have to undergo lower limb amputation. In Sushruta Samhita, we get the most scientific descriptions of wound and their management. Similarly, Sushruta has given the utmost importance to Kshara application in Diabetes foot ulcer. Patient with Diabetes foot ulcer was advised to continue anti diabetes medicines along with weekly application of Achyrenthus aspera alkali powder. This Kshara application proved very effective and the ulcer healed completely with 40 days. With Kshara application the wound completely healed within 40 days. Whereas statistic reveals that about 30% of Diabetes Mellitus neuropathic ulcer receiving standard care requires around 20 weeks for healing. Thus Kshara application proves to be effective, time saving affordable and acceptable treatment. Though treating Diabetes foot is a difficult task, we have managed to treat with Kshara application along with conventional (Ayulwedic) methods of wound care. However, further evaluation is required to be done by taking a large sample size to prove its significance in healing Diabetes foot ulcer and avoiding lower limb amputation.
A Case Study on the Ayurvedic Management of Varicose Vein
(1st International Conference and Exhibition in Indigenous Medicine – ICEIM – 2018, Organized by Indigenous Medicine, Eastern Province with the collaboration of Unit of Siddha Medicine, Trincomalee Campus, Eastern University of Sri Lanka, 2018) Samaranayake, G.V.P.; Pushpakumara, A.A.J.
A Condition, in which a vein becomes dilated, elongated and tortuous, this is said to be "Varicose". There are primary as well as secondary causes of varicose veins. The superficial perforating as well as the deep veins are involved in varicose veins. The contemporary treatment for varicose veins includes ligation, ligation with stripping surgical treatments. But these treatments can cause reoccurrence of this disease. Ayurveda reveal Siravedha (venesection) cures varicose veins. We hereby report a case of a 60-year-old female with complaints of pain in the lower limbs from calf to the dorsum of the foot of both legs associated with dilated and tortuous veins in the anterior aspect of lower leg with discoloration. She was advised admission for ten days and was treated with internal medication, external treatments and Siravedha (venesection). During the treatment all the signs and symptoms of varicosity reduced to a very high extend. As the case showed significant changes in the symptoms of pain, swelling, burning sensation and dilated veins with discoloration, during the ten days of treatment with internal medicines as well as Siravedha done for 3 alternate day. It can be concluded that in such conditions of varicose vein, Rakta mokshana along with Raktaprasadana drugs will be choice of treatment. A large-scale clinical study should be conducted to evaluate the efficacy and benefits of this modality of treatment with longer follow ups.
Clinical evaluation of Passiflora foetida decoction in the management of Urolithiasis
(International symposium on Traditional and Complementary Medicine of the Tradmed International 2017-Sri Lanka organized by Ministry of Health, Nutrition & Indigenous Medicine and Department of Ayurveda Sri Lanka, @ Waters Edge, Battaramulla, Sri Lanka, 2017) Samaranayake, G.V.P.; Pushpakumara, A.A.J.
In the present study an effort was made to evaluate the efficacy of a decoction of the whole plant Passiflora foetida. The main aim Of this particular study was inclined towards the disintegration, dissolution, dislodgement and expulsion of renal stones. These drugs are easily available, economical and easy to administer, and also have anti-inflammatory, diuretic and anti-lithic properties. A total Of 30 patients were selected randomly and were divided in to two groups. Each group contained IS patients. Group-I was treated with the decoction Of Passiflora foetida at a dose Of 45 ml, twice daily, after food for a period of 45 days. Group-Il was treated with Flush out therapy (hydro-therapy). The efficacy of decoction of Passiflora foetida in the relief of pain (76%), haematuria (83%), dysuria (76%), size of calculi (74%) and number of calculi (68.7%) was highly significant. Hence this study suggests that traditional Ayurvedic management is effective and did not have any obvious adverse effects on the patients with Urolithiasis.
Clinical Evaluation of Polyherbal Ayurvedic Formula (PHAF) in the management of Acne vulgaris
(World Journal of Pharmaceutical and Life Sciences (WJPLS), 2018) Samaranayake, G.V.P.; Pushpakumara, A.A.J.
Acne vulgaris is the most common disease among young generation. A preliminary trail was conducted in the Shalya Clinic in Gampaha Wickramarachchi Ayurvedic Hospital, to assess the safety and efficacy of a Polyherbal Ayurvedic Formulation in the management of Acne vulgaris on scientific parameter. Twenty five patient were clinically assessed and diagnosed on the basis of thorough history. Then polyherbal Ayurvedic Formulation was administered locally once at night for a period of 45 days. The severity of acne and efficacy of treatment was assessed by Cook's acne grading scale. The results showed significant reduction in the Cook's acne grading Scores of post-treatment group ) as compared to pre-treatment scores. Further, Polyherbal Ayurvedic Formula was found safe and fairly well accepted by the patient- It was therefore concluded that Polyherbal Ayurvedic Formulation can be used safely and effectively for the treatment Of Acne vulgaris
Clinical evaluation of the efficacy of Prathis (Plasta) in the management of Haemorrhoids
(Bandaranaike Memorial Ayurvedic Research Institute, Navinna, Maharagama, 2015) Rajapakse, T.S.; Pushpakumara, A.A.J.
Clinical Study of a selected indegenous decoction (Rathulunu kalan 06) in the management of Raktarsas (bleeding piles).
(Pandit G.P. Wickramarachchi Memorial International Research Symposium 2012, 2012) Kaldera, H.P.I.J.; Pushpakumara, A.A.J.
Hemorrhoids are the enlarged, bulging veins in the rectum. The main causes for this disease are the bad food habits and health habits of the people. It is recorded that 4% of the world's population are suffering from the hemorrhoids. Blccding from rectum, anal itching, occasional pain, burning sensation arc the common symptoms of the hemorrhoids. According to Ayurvedic Medicine; bleeding piles are called 'Raklarsas'. This decoction mentioned in "Desheeya Cikitsa Samgrahaya". This clinical study was conducted to evaluate the effectiveness of the above decoction in the management Of Raktarsas. Analyzed 30 Cases Of Rakrarsas in people, between 20 to 70 of age , who had complained of bleeding from rectum, constipation. burning sensation and pain in the rectum. They wcrc equally and randomly put into two groups; "Group A" and "Group B". ne "GroupA" was treated with 120ml of the selected decoction twice a day, 30ml Of the mixture Of Abhayarishla and Danthyarishla twice a day after the meal, 30g Of Sukumarachoorna With 240m' Of warm water before bed time and the external application Of the Sarvavishadi oil on the hemorrhoids twice a day for 3 weeks while the "Group B" was given the above prescription without the decoction. The effectiveness of the selected decoction was evaluated on the basis of clinical data. The results of thc trcatmcnt wcrc calculated by using the P-value. Statistically more significant results were observed in Group A than in Group B. According to this clinical study it was revealed that the selected decoction is one of the most effective treatments for Raktarsas.
Clinical study of the efficacy of a selected indigenous decoction (Rathulunukalan 06) in the management of Raktarsas (Bleeding piles)
(Gampaha Wickramarachchi Ayurveda Institute, 2012) Kaldera, H.P.I.J.; Pushpakumara, A.A.J.
A clinical study on the efficacy of Triphal-Kihiri, a traditional formula, on the management of chronic wounds
(Gampaha Wickramarachchi Ayurveda Institute, 2012) Eranga, K.K.I.; Perera, B.S.R.; Pushpakumara, A.A.J.
Comparative antibacterial screening on Biophylum sensitivum and Mimosa pudica for diabetic foot ulcer
(Institute of Indigenous medicine, University of Colombo, Rajagiriya, Sri Lanka., 2014) Kularathna, D.P.D.N.; Pushpakumara, A.A.J.; Dayarathna, M.T.A.
Comparative assessment of Jalaukavacharana (Hirudotherapy) and Siravyadha (Venepuncture) in the management of chronic venous ulcers
(Institute of Indigenous medicine, University of Colombo, Rajagiriya, Sri Lanka, 2015) Kularathna, D.P.D.N.; Pushpakumara, A.A.J.
Comparative Clinical Study of Efficacy of Seethodaka Oil & Dashanga Lepa in the Management of Chronic Wounds
(2nd International Research Conference & Exhibition on Siddha Medicine -2020, Organized by Unit of Siddha Medicine, University of Jaffna, Kaithady, Sri Lanka, 2020) Samaranayake, G.V.P.; Pushpakumara, A.A.J.
Wound healing is a complex and dynamic process with the wound environment changing with the changing health status of the individual. The knowledge of the physiology of the nonnal wound healing trajectory through the phases of haemostasis, inflammation, granulation and maturation provides a framework for an understanding of the basic principles of wound healing. Through this understanding the health care professional can develop the skills required to care for a wound and the body can be assisted in the complex task of tissue repair. A chronic wound should prompt the health care professional to begin a search for unresolved underlying causes. Healing a chronic wound requires care that is patient centered, holistic, interdisciplinary, costeffective and evidence based. Forty patients with varicose ulcer were enrolled in this comparative clinical study. For each group twenty patients were selected randomly, informed consent was attained and then they underwent treatment with either Seethodaka oil or Dashanga Lepa for dressing daily for 8 weeks. The follow up duration was minimally I -2 months. In the study percentage of 57.5% male and 42.5% female patients in the sample Age group of 30 to 40 years 20%, 41 to 50 years 32.5% and 51 to 60 years 47.5% of patients were chronic ulcers with different wound size, pain and other criterias in the two groups. P values of group A (P=O.005) > P values of group B (P = 0.000), therefore reduction of the wound size in the Group B (Dashanga Lepa) is more significant than Group A (Seethodaka oil). It was concluded that the application of Dashanga Lepa can be used more effective than Seethodaka oil on healing of the wound management.
Comparative study on different treatment modules in the management of Fistula – In - Ano (Bhagandara)
(International Journal of Current Advanced Research, 2020) Samaranayake, G.V.P.; Pushpakumara, A.A.J.; Peiris, K.P.P.
Bhagandara is a common disease occurring in the ano-rectal region. Acharya Susruta, the father of surgery has included this disease as one among the Ashtamahagada. It can be correlated with Fistula-in-ano as described in western medical science. Fistula-in-ano is a track lined by granulation tissue which opens deeply in the anal canal or rectum and superficially on the skin around the anus. The incidence of a Fistula-in-ano developing from an anal abscess ranges from 26-38%. The prevalence in men is 12.3 cases per 100 ,000 populations and in women are 5.6 cases per 100,000 populations. The male to female ratio is 1.8: l. The mean age of patients is 38.3 years. This randomized prospective cohort clinical study was done to compare and evaluate the effect of new herbal formulation consisting of Vitex nigundo(root), Crativa adansoni (bark), Ricinus communis (bark), Plumbago indica(root) in managing fistula-in-ano conditions of patients in comparison to the effect of tripala decoction and kshara sutra. The patients were selected according to the selection criteria and randomly assign in to 2 groups (Group A, Group B) consisting of 20 patients for each. The patients of Group A was be treated with, Tripala decoction, kshara sutra and prescribed dietary management. The patients of group B were treated with, new herbal formulation, kshara sutra and prescribed dietary management during the period of 8 weeks. In the group A and group B mean changes or decrement of pain, burning sensation, itching and discharge, P values = 0.00 95% confidence level P < 0.05 both groups are same P=O.()()O. Therefore, no difference between both groups and it shows statistically significant. In the group A mean decrement of length of the fistulous track P value p = 0.005 at confidence level P < 0.05. It shows a significant decrement of the length of fistulous track statistically in 95% confidence level. In the group B mean decrement of length of fistulous track P value p = 0.000 at 95% confidence level P < 0.05. It shows a significant decrement of the length of fistulous track statistically in 95% confidence level. But mean decrement of length of fistulous track of the group B greater than that of group A, which means group B more statistically significant. Finally, based on the observed results and the pharmacodynamic properties of both treatment protocols, it may be concluded that new herbal formulation + kshara sutra + dietary management treatment module is more effective than Tripala decoction + kshara sutra + dietary management in the management of fistula-in-ano.